Your browser doesn't support javascript.
Investigation of plasma exchange and hemoperfusion effects and complications for the treatment of patients with severe COVID-19 (SARS-CoV-2) disease: A systematic scoping review.
Mousavi-Roknabadi, Razieh Sadat; Haddad, Fatemeh; Fazlzadeh, Aylar; Kheirabadi, Dorna; Dehghan, Hamidreza; Rezaeisadrabadi, Mohammad.
  • Mousavi-Roknabadi RS; Department of Emergency Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Haddad F; Emergency Medicine Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Fazlzadeh A; Department of Medical Physiology, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Kheirabadi D; Department of Internal Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Dehghan H; Department of Anesthesiology and Critical Care, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
  • Rezaeisadrabadi M; Department of Biostatistics, Research Center for Health Technology Assessment and Medical Informatics, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
J Med Virol ; 93(10): 5742-5755, 2021 Oct.
Article in English | MEDLINE | ID: covidwho-1296839
ABSTRACT
Some previous studies suggested that the plasma exchange (PE) and hemoperfusion (HP) played a cardinal role in the treatment of severe coronavirus disease 2019 (COVID-19) cases by diminishing the cytokine storm. This study aimed to assess the effects of PE and HP on cytokine storms in patients with severe COVID-19 through a systematic scoping review. Four Electronic databases (Medline [accessed from PubMed], Scopus, Science Direct, and Cochrane library) were searched systematically on February 2, 2021, using MESH terms and related keywords in the English language. Considering the titles and abstracts, unrelated studies were excluded. The full texts of the remained studies were evaluated by authors, independently. Then, their findings were assessed and reported. A total of 755 articles were obtained within the first step of searching, and 518 remained after removing the duplications. Through the title and abstract screening, 438 were removed. Of the rest, 59 papers were excluded. Finally, after reading the full text of the remained articles, 21 were included in data extraction. Most of the previously reported evidence were case reports and case series. Findings were summarized in two categories. The first category encompassed nine studies regarding HP and continuous renal replacement therapy, and the second category included twelve studies about PE. The results revealed that HP and PE within the cytokine storm phase would be beneficial with a high probability in the treatment of severely ill COVID-19 patients. Highlights Some studies showed that plasma exchange (PE) and hemoperfusion (HP) played an important role in the treatment of patients with severe COVID-19 disease. The results of this systematic scoping review revealed that HP and PE within the cytokine storm phase would be beneficial with a high probability in the treatment of severely ill COVID-19 patients.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Plasma Exchange / Hemoperfusion / COVID-19 Type of study: Experimental Studies / Prognostic study / Reviews / Systematic review/Meta Analysis Limits: Humans Language: English Journal: J Med Virol Year: 2021 Document Type: Article Affiliation country: Jmv.27182

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Plasma Exchange / Hemoperfusion / COVID-19 Type of study: Experimental Studies / Prognostic study / Reviews / Systematic review/Meta Analysis Limits: Humans Language: English Journal: J Med Virol Year: 2021 Document Type: Article Affiliation country: Jmv.27182