Your browser doesn't support javascript.
Clinical characteristics of patients with COVID-19 combined with cardiovascular disease
Medical Journal of Wuhan University ; 42(4):599-602, 2021.
Article in Chinese | Scopus | ID: covidwho-1299709
ABSTRACT

Objective:

To retrospectively analyze the clinical characteristics of coronavirus disease 2019 (COVID-19) and the impact of cardiovascular disease (CVD) on the clinical manifestations of COVID-19.

Methods:

A total of 128 patients diagnosed with COVID-19 in Renmin Hospital of Wuhan University from February 1 to February 29, 2020 were divided into CVD group (n=62) and non-CVD group (n=66). The general data, admission symptoms and laboratory examination results including blood routine, immunity, heart, liver and kidney function were obtained and statistically analyzed by SPSS 22.0 statistical software. The differences of various indexes between CVD group and non-CVD group were compared.

Results:

There was no significant difference in gender between CVD group and non-CVD group(P>0.05).The average age of CVD group was higher than that of non-CVD group (P<0.001). The proportion of fever and cough, severe and critical patients was higher than that respectively of non-CVD group (all P<0.05). There was no significant difference in the incidence of fatigue, dyspnea, and asymptomatic between the two groups (all P>0.05). The average levels of eukocyte count, neutrophil ratio, neutrophil count, monocyte count, and C-reactive protein in CVD group were higher than those in non-CVD group (all P<0.05), while the average lymphocyte proportion in CVD group was lower than that in non-CVD group (P<0.05). There was no significant difference in lymphocyte count and platelet count between the two groups (both P>0.05). The average LDH, myohemoglobin, CK-MB, NT-proBNP, TBIL, and Urea in CVD group were higher than those in non-CVD group (all P<0.05), but there was no significant difference in ALT, AST, and Cr between the two groups (all P>0.05).

Conclusion:

Compared with non-CVD patients with COVID-19, CVD patients with COVID-19 are older, have more obvious symptoms, with a higher risksin heart, liver, and kidney injury, but the mechanism is not clear yet. © 2021, Editorial Board of Medical Journal of Wuhan University. All right reserved.

Full text: Available Collection: Databases of international organizations Database: Scopus Type of study: Prognostic study Language: Chinese Journal: Medical Journal of Wuhan University Year: 2021 Document Type: Article

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: Databases of international organizations Database: Scopus Type of study: Prognostic study Language: Chinese Journal: Medical Journal of Wuhan University Year: 2021 Document Type: Article