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Epidemiologic Features, Radiological Findings andClinical Outcomes of 19 Patients with COVID-19in a Single Center in Beijing, China.
Song, Lan; Zhu, Zhen Chen; Zhao, Rui Jie; Li, Peng Chang; Tian, Du Xue; Du, Tie Kuan; Xu, Yan; Yang, Qiwen; Cao, Wei; Song, Wei; Jin, Zheng Yu.
  • Song L; Department of Radiology,Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
  • Zhu ZC; Department of Radiology,Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
  • Zhao RJ; MD Program, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
  • Li PC; Department of Radiology,Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
  • Tian DX; Department of Laboratory Medicine,Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
  • Du TK; Department of Radiology,Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
  • Xu Y; Department of Emergency,Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
  • Yang Q; Department of Respiratory and Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
  • Cao W; Department of Laboratory Medicine,Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
  • Song W; Department of Infectious Disease, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
  • Jin ZY; Department of Radiology,Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
Chin Med Sci J ; 36(2): 85-96, 2021 Jun 30.
Article in English | MEDLINE | ID: covidwho-1299806
ABSTRACT
ObjectiveTo describe the epidemiologic, clinical, laboratory, and radiological characteristics and prognoses of COVID-19 confirmed patients in a single center in Beijing, China. Methods The study retrospectively included 19 patients with nucleic acid-confirmed SARS-CoV-2 infection at our hospital from January 20 to March 5, 2020. The final follow-up date was March 14, 2020. The epidemiologic and clinical information was obtained through direct communication with the patients or their family members. Laboratory results retrieved from medical records and radiological images were analyzed both qualitatively by two senior chest radiologists as well as quantitatively via an artificial intelligence software. Results We identified 5 family clusters (13/19, 68.4%) from the study cohort. All cases had good clinical prognoses and were either mild (3/19) or moderate (16/19) clinical types. Fever (15/19, 78.9%) and dry cough (11/19, 57.9%) were common symptoms. Two patients received negative results for more than three consecutive viral nucleic acid tests. The longest interval between an initial CT abnormal finding and a confirmed diagnosis was 30 days. One patient's nucleic acid test turned positive on the follow-up examination after discharge. The presence of radiological abnormalities was non-specific for the diagnosis of COVID-19. Conclusions COVID-19 patients with mild or no clinical symptoms are common in Beijing, China. Radiological abnormalities are mostly non-specific and massive CT examinations for COVID-19 screening should be avoided. Analyses of the contact histories of diagnosed cases in combination with clinical, radiological and laboratory findings are crucial for the early detection of COVID-19. Close monitoring after discharge is also recommended.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Tomography, X-Ray Computed / COVID-19 Nucleic Acid Testing / SARS-CoV-2 / COVID-19 / Lung Type of study: Cohort study / Diagnostic study / Observational study / Prognostic study / Qualitative research Limits: Adult / Child / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: English Journal: Chin Med Sci J Journal subject: Complementary Therapies Year: 2021 Document Type: Article Affiliation country: 003821

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Tomography, X-Ray Computed / COVID-19 Nucleic Acid Testing / SARS-CoV-2 / COVID-19 / Lung Type of study: Cohort study / Diagnostic study / Observational study / Prognostic study / Qualitative research Limits: Adult / Child / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: English Journal: Chin Med Sci J Journal subject: Complementary Therapies Year: 2021 Document Type: Article Affiliation country: 003821