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Impact of the COVID-19 Pandemic on Cancer Clinical Trials.
Boughey, Judy C; Snyder, Rebecca A; Kantor, Olga; Zheng, Linda; Chawla, Akhil; Nguyen, Toan T; Hillman, Shauna L; Hahn, Olwen M; Mandrekar, Sumithra J; Roland, Christina L.
  • Boughey JC; Department of Surgery, Mayo Clinic, Rochester, MN, USA. Boughey.judy@mayo.edu.
  • Snyder RA; Division of Surgical Oncology, East Carolina University Brody School of Medicine, Greenville, NC, USA.
  • Kantor O; Division of Breast Surgery, Department of Surgery, Brigham and Women's Hospital, Boston, MA, USA.
  • Zheng L; American College of Surgeons Cancer Research Program, Chicago, IL, USA.
  • Chawla A; Division of Surgical Oncology, Department of Surgery, Northwestern Medicine Regional Medical Group, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
  • Nguyen TT; Lakeland Regional Health, Lakeland, FL, USA.
  • Hillman SL; Department of Health Sciences Research, Alliance Statistics and Data Management Center, Mayo Clinic, Rochester, MN, USA.
  • Hahn OM; Alliance Protocol Operations Office, University of Chicago, Chicago, IL, USA.
  • Mandrekar SJ; Department of Health Sciences Research, Alliance Statistics and Data Management Center, Mayo Clinic, Rochester, MN, USA.
  • Roland CL; Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Ann Surg Oncol ; 28(12): 7311-7316, 2021 Nov.
Article in English | MEDLINE | ID: covidwho-1301912
ABSTRACT
The COVID-19 pandemic has had widespread impact on healthcare, resulting in modifications to how we perform cancer research, including clinical trials for cancer. The impact of some healthcare workers and study coordinators working remotely and patients minimizing visits to medical facilities impacted clinical trial participation. Clinical trial accrual dropped at the onset of the pandemic, with improvement over time. Adjustments were made to some trial protocols, allowing telephone or video-enabled consent. Certain study activities were permitted to be performed by local healthcare providers or at local laboratories to maximize patients' ability to continue on study during these challenging times. We discuss the impact of COVID-19 on cancer clinical trials and changes at the local, cooperative group, and national level.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / Neoplasms Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Humans Language: English Journal: Ann Surg Oncol Journal subject: Neoplasms Year: 2021 Document Type: Article Affiliation country: S10434-021-10406-2

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / Neoplasms Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Humans Language: English Journal: Ann Surg Oncol Journal subject: Neoplasms Year: 2021 Document Type: Article Affiliation country: S10434-021-10406-2