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Fecal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-Cov-2) RNA Is Associated With Decreased Coronavirus Disease 2019 (COVID-19) Survival.
Das Adhikari, Upasana; Eng, George; Farcasanu, Mara; Avena, Laura E; Choudhary, Manish C; Triant, Virginia A; Flagg, Meaghan; Schiff, Abigail E; Gomez, Isabella; Froehle, Leah M; Diefenbach, Thomas J; Ronsard, Larance; Lingwood, Daniel; Lee, Grace C; Rabi, Seyed Alireza; Erstad, Derek; Velmahos, George; Li, Jonathan Z; Hodin, Richard; Stone, James R; Honko, Anna N; Griffiths, Anthony; Yilmaz, Ömer H; Kwon, Douglas S.
  • Das Adhikari U; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Cambridge, Massachusetts, USA.
  • Eng G; Harvard Medical School, Boston, Massachusetts, USA.
  • Farcasanu M; Harvard Medical School, Boston, Massachusetts, USA.
  • Avena LE; Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Choudhary MC; Koch Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
  • Triant VA; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Cambridge, Massachusetts, USA.
  • Flagg M; Harvard Medical School, Boston, Massachusetts, USA.
  • Schiff AE; Department of Microbiology and National Emerging Infectious Diseases Laboratories, Boston University School of Medicine, Boston, Massachusetts, USA.
  • Gomez I; Division of Infectious Diseases, Brigham and Women's Hospital, Boston, Massachusetts, USA.
  • Froehle LM; Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Diefenbach TJ; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Cambridge, Massachusetts, USA.
  • Ronsard L; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Cambridge, Massachusetts, USA.
  • Lingwood D; Harvard Medical School, Boston, Massachusetts, USA.
  • Lee GC; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Cambridge, Massachusetts, USA.
  • Rabi SA; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Cambridge, Massachusetts, USA.
  • Erstad D; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Cambridge, Massachusetts, USA.
  • Velmahos G; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Cambridge, Massachusetts, USA.
  • Li JZ; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Cambridge, Massachusetts, USA.
  • Hodin R; Division of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Stone JR; Division of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Honko AN; Division of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Griffiths A; Division of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Yilmaz ÖH; Harvard Medical School, Boston, Massachusetts, USA.
  • Kwon DS; Division of Infectious Diseases, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Clin Infect Dis ; 74(6): 1081-1084, 2022 03 23.
Article in English | MEDLINE | ID: covidwho-1303899
ABSTRACT
The clinical significance of severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) RNA in stool remains uncertain. We found that extrapulmonary dissemination of infection to the gastrointestinal tract, assessed by the presence of SARS-CoV-2 RNA in stool, is associated with decreased coronavirus disease 2019 (COVID-19) survival. Measurement of SARS-CoV-2 RNA in stool may have utility for clinical risk assessment.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Risk factors Limits: Humans Language: English Journal: Clin Infect Dis Journal subject: Communicable Diseases Year: 2022 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Risk factors Limits: Humans Language: English Journal: Clin Infect Dis Journal subject: Communicable Diseases Year: 2022 Document Type: Article