Hyperacute reversible encephalopathy related to cytokine storm following COVID-19 vaccine.
J Neuroimmunol
; 358: 577661, 2021 09 15.
Article
in English
| MEDLINE | ID: covidwho-1307055
ABSTRACT
We describe the first case of hyperacute reversible encephalopathy following COVID-19 vaccination. A patient presented with acute onset encephalopathy, mainly characterized by agitation and confusion, rapidly responsive to high dosage steroid therapy and complete remission within 3 days from onset. The clinical manifestation was related with systemic and CSF cytokine hyperproduction, responsive to steroid therapy. Although the occurrence of encephalopathy after vaccination may be just a casual temporal association, we speculate that the cytokine-storm could be the result of an excessive innate immune response against the vaccine, in a predisposed patient susceptible to autoimmunity.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Brain Diseases
/
Cytokine Release Syndrome
/
COVID-19 Vaccines
Type of study:
Case report
/
Prognostic study
Topics:
Vaccines
Limits:
Aged
/
Humans
/
Male
Language:
English
Journal:
J Neuroimmunol
Year:
2021
Document Type:
Article
Affiliation country:
J.jneuroim.2021.577661
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