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Endophthalmitis Rate in Immediately Sequential versus Delayed Sequential Bilateral Cataract Surgery within the Intelligent Research in Sight (IRIS®) Registry Data.
Lacy, Megan; Kung, Timothy-Paul H; Owen, Julia P; Yanagihara, Ryan T; Blazes, Marian; Pershing, Suzann; Hyman, Leslie G; Van Gelder, Russell N; Lee, Aaron Y; Lee, Cecilia S.
  • Lacy M; Department of Ophthalmology, University of Washington, Seattle, Washington.
  • Kung TH; Department of Ophthalmology, University of Washington, Seattle, Washington; Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, New York.
  • Owen JP; Department of Ophthalmology, University of Washington, Seattle, Washington.
  • Yanagihara RT; Department of Ophthalmology, University of Washington, Seattle, Washington.
  • Blazes M; Department of Ophthalmology, University of Washington, Seattle, Washington.
  • Pershing S; Department of Ophthalmology, Byers Eye Institute, Stanford University, Palo Alto, California; Veterans Affairs Palo Alto Health California System, Palo Alto, California.
  • Hyman LG; The Vision Research Center, Wills Eye Hospital, Philadelphia, Pennsylvania.
  • Van Gelder RN; Department of Ophthalmology, University of Washington, Seattle, Washington; Roger and Angie Karalis Johnson Retina Center, Seattle, Washington.
  • Lee AY; Department of Ophthalmology, University of Washington, Seattle, Washington; Roger and Angie Karalis Johnson Retina Center, Seattle, Washington.
  • Lee CS; Department of Ophthalmology, University of Washington, Seattle, Washington; Roger and Angie Karalis Johnson Retina Center, Seattle, Washington. Electronic address: leecs2@uw.edu.
Ophthalmology ; 129(2): 129-138, 2022 02.
Article in English | MEDLINE | ID: covidwho-1307126
ABSTRACT

PURPOSE:

To compare the rate of postoperative endophthalmitis after immediately sequential bilateral cataract surgery (ISBCS) versus delayed sequential bilateral cataract surgery (DSBCS) using the American Academy of Ophthalmology Intelligent Research in Sight (IRIS®) Registry database.

DESIGN:

Retrospective cohort study.

PARTICIPANTS:

Patients in the IRIS Registry who underwent cataract surgery from 2013 through 2018.

METHODS:

Patients who underwent cataract surgery were divided into 2 groups (1) ISBCS and (2) DSBCS (second-eye surgery ≥1 day after the first-eye surgery) or unilateral surgery. Postoperative endophthalmitis was defined as endophthalmitis occurring within 4 weeks of surgery by International Classification of Diseases (ICD) code and ICD code with additional clinical criteria. MAIN OUTCOME

MEASURES:

Rate of postoperative endophthalmitis.

RESULTS:

Of 5 573 639 IRIS Registry patients who underwent cataract extraction, 165 609 underwent ISBCS, and 5 408 030 underwent DSBCS or unilateral surgery (3 695 440 DSBCS, 1 712 590 unilateral surgery only). A total of 3102 participants (0.056%) met study criteria of postoperative endophthalmitis with supporting clinical findings. The rates of endophthalmitis in either surgery eye between the 2 surgery groups were similar (0.059% in the ISBCS group vs. 0.056% in the DSBCS or unilateral group; P = 0.53). Although the incidence of endophthalmitis was slightly higher in the ISBCS group compared with the DSBCS or unilateral group, the odds ratio did not reach statistical significance (1.08; 95% confidence interval, 0.87-1.31; P = 0.47) after adjusting for age, sex, race, insurance status, and comorbid eye disease. Seven cases of bilateral endophthalmitis with supporting clinical data in the DSBCS group and no cases in the ISBCS group were identified.

CONCLUSIONS:

Risk of postoperative endophthalmitis was not statistically significantly different between patients who underwent ISBCS and DSBCS or unilateral cataract surgery.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Postoperative Complications / Cataract Extraction / Visual Acuity / Registries / Endophthalmitis / Lens Implantation, Intraocular Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged Country/Region as subject: North America Language: English Journal: Ophthalmology Year: 2022 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Postoperative Complications / Cataract Extraction / Visual Acuity / Registries / Endophthalmitis / Lens Implantation, Intraocular Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged Country/Region as subject: North America Language: English Journal: Ophthalmology Year: 2022 Document Type: Article