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Pandemic of the aging society - sporadic cerebral small vessel disease.
Lau, Alexander Yuk Lun; Ip, Bonaventure Yiu Ming; Ko, Ho; Lam, Bonnie Yin Ka; Shi, Lin; Ma, Karen Ka Yan; Au, Lisa Wing Chi; Soo, Yannie Oi Yan; Leung, Thomas Wai Hong; Wong, Adrian; Mok, Vincent Chung Tong.
  • Lau AYL; Division of Neurology, Department of Medicine and Therapeutics, The Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
  • Ip BYM; Gerald Choa Neuroscience Centre, Faculty of Medicine, Lui Che Woo Institute of Innovative Medicine, The Chinese University of Hong Kong, Hong Kong, China.
  • Ko H; Division of Neurology, Department of Medicine and Therapeutics, The Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
  • Lam BYK; Division of Neurology, Department of Medicine and Therapeutics, The Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
  • Shi L; Gerald Choa Neuroscience Centre, Faculty of Medicine, Lui Che Woo Institute of Innovative Medicine, The Chinese University of Hong Kong, Hong Kong, China.
  • Ma KKY; Faculty of Medicine, School of Biomedical Sciences, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.
  • Au LWC; Margaret Cheung K. L. Cheung Research Centre for Management of Parkinsonism, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
  • Soo YOY; Division of Neurology, Department of Medicine and Therapeutics, The Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
  • Leung TWH; Gerald Choa Neuroscience Centre, Faculty of Medicine, Lui Che Woo Institute of Innovative Medicine, The Chinese University of Hong Kong, Hong Kong, China.
  • Wong A; Margaret Cheung K. L. Cheung Research Centre for Management of Parkinsonism, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
  • Mok VCT; Department of Imaging and Interventional Radiology, The Chinese University of Hong Kong, Hong Kong, China.
Chin Med J (Engl) ; 134(2): 143-150, 2021 01 05.
Article in English | MEDLINE | ID: covidwho-1307571
ABSTRACT
ABSTRACT Age-related sporadic cerebral small vessel disease (CSVD) has gained increasing attention over the past decades because of its increasing prevalence associated with an aging population. The widespread application of and advances in brain magnetic resonance imaging in recent decades have significantly increased researchers' understanding in the in vivo evolution of CSVD, its impact upon the brain, its risk factors, and the mechanisms that explain the various clinical manifestation associated with sporadic CSVD. In this review, we aimed to provide an update on the pathophysiology, risk factors, biomarkers, and the determinants and spectrum of the clinical manifestation of sporadic CSVD.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pandemics / Cerebral Small Vessel Diseases Type of study: Observational study / Prognostic study Limits: Aged / Humans Language: English Journal: Chin Med J (Engl) Year: 2021 Document Type: Article Affiliation country: CM9.0000000000001320

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pandemics / Cerebral Small Vessel Diseases Type of study: Observational study / Prognostic study Limits: Aged / Humans Language: English Journal: Chin Med J (Engl) Year: 2021 Document Type: Article Affiliation country: CM9.0000000000001320