Risk Factors of SARS-CoV-2 Antibodies in Arapahoe County First Responders-The COVID-19 Arapahoe SErosurveillance Study (CASES) Project.
J Occup Environ Med
; 63(3): 191-198, 2021 03 01.
Article
in English
| MEDLINE | ID: covidwho-1307590
ABSTRACT
OBJECTIVES:
Define the seroprevalence and risk factors for SARS-CoV-2 antibodies in Arapahoe County, Colorado first responders (eg, law enforcement, human services, fire departments).METHODS:
Two hundred sixty four first responders were enrolled June to July 2020. SARS-CoV-2 seropositivity was defined as detection of immunoglobulin G (IgG) antibodies to both spike receptor binding domain and nucleocapsid in venous blood by validated enzyme-linked immunosorbent assay. We compared risk factors for being seropositive versus seronegative.RESULTS:
4% (11/264) were SARS-CoV-2 seropositive. Seropositive participants were significantly more likely to have lung disease (% seropositive, % seronegative; P-value) (36%, 8%; Pâ=â0.01), prior SARS-CoV-2/COVID-19 testing (36%, 8%; Pâ≤â0.01), a prior positive result (18%, less than 1%), and to believe they previously had COVID-19 (64%, 15%; Pâ<â0.01). Only 15% of those believing they had COVID-19 had anti-SARS-CoV-2 antibodies.CONCLUSIONS:
Human services employees and individuals with lung disease are at SARS-CoV-2 exposure risk. Few individuals believed they had COVID-19 had prior exposure.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Emergency Responders
/
SARS-CoV-2
/
COVID-19
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
Limits:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
North America
Language:
English
Journal:
J Occup Environ Med
Journal subject:
Occupational Medicine
/
Environmental Health
Year:
2021
Document Type:
Article
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