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Transplant of SARS-CoV-2-infected Living Donor Liver: Case Report.
Nguyen, Michelle C; Lee, Eliza J; Avery, Robin K; Dioverti-Prono, M Veronica; Shoham, Shmuel; Tobian, Aaron A R; Bloch, Evan M; Gurakar, Ahmet; Rizkalla, Nicole A; Cameron, Andrew M; King, Elizabeth A; Ottmann, Shane; Garonzik-Wang, Jacqueline M; Wesson, Russel N; Philosophe, Benjamin.
  • Nguyen MC; Division of Transplant Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Lee EJ; Division of Transplant Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Avery RK; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Dioverti-Prono MV; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Shoham S; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Tobian AAR; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Bloch EM; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Gurakar A; Division of Gastroenterology and Hepatology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD.
  • Rizkalla NA; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Cameron AM; Division of Transplant Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
  • King EA; Department of Epidemiology, Johns Hopkins School of Public Health, Baltimore, MD.
  • Ottmann S; Division of Transplant Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Garonzik-Wang JM; Division of Transplant Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Wesson RN; Division of Transplant Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
  • Philosophe B; Department of Epidemiology, Johns Hopkins School of Public Health, Baltimore, MD.
Transplant Direct ; 7(8): e721, 2021 Aug.
Article in English | MEDLINE | ID: covidwho-1309678
ABSTRACT
Given the high community prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), transplant programs will encounter SARS-CoV-2 infections in living donors or recipients in the perioperative period. There is limited data on SARS-CoV-2 viremia and organotropism beyond the respiratory tract to inform the risk of transplant transmission of SARS-CoV-2. We report a case of a living donor liver transplant recipient who received a right lobe graft from a living donor with symptomatic PCR-confirmed SARS-CoV-2 infection 3 d following donation. The donor was successfully treated with remdesivir, dexamethasone, and coronavirus disease 2019 (COVID-19) convalescent plasma. No viral transmission was identified, and both donor and recipient had excellent postoperative outcomes.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report / Observational study / Prognostic study Language: English Journal: Transplant Direct Year: 2021 Document Type: Article Affiliation country: Txd.0000000000001178

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report / Observational study / Prognostic study Language: English Journal: Transplant Direct Year: 2021 Document Type: Article Affiliation country: Txd.0000000000001178