Your browser doesn't support javascript.
Tofacitinib as an Adjunct Immunomodulator for Treatment of a Patient with Severe COVID-19: A Case Report.
Shrestha, Gentle Sunder; Bista, Bidesh; Dhungana, Ashesh; Poudel, Nimesh; Bhattarai, Shraddha; Shrestha, Manjit; Bhandari, Sandip; Vaidya, Binit.
  • Shrestha GS; Department of Anaesthesiology, Tribhuvan University Teaching Hospital, Kathmandu.
  • Bista B; Department of Internal Medicine, Civil Service Hospital of Nepal, Kathmandu, Nepal.
  • Dhungana A; Department of Internal Medicine, National Academy of Medical Sciences, Bir Hospital, Kathmandu, Nepal.
  • Poudel N; Department of Internal Medicine, Kathmandu Medical College and Teaching Hospital, Kathmandu, Nepal.
  • Bhattarai S; Department of Critical Care Medicine, Alka Hospital Pvt. Ltd, Lalitpur, Nepal.
  • Shrestha M; Department of Critical Care Medicine, Alka Hospital Pvt. Ltd, Lalitpur, Nepal.
  • Bhandari S; Department of Anaesthesiology, Shahid Gangalal National Heart Centre, Kathmandu, Nepal.
  • Vaidya B; Department of Rheumatology, National Center for Rheumatic Diseases, Kathmandu, Nepal.
JNMA J Nepal Med Assoc ; 59(238): 593-596, 2021 Jul 01.
Article in English | MEDLINE | ID: covidwho-1310357
ABSTRACT
Severe coronavirus disease 2019 can be associated with progressive respiratory failure. In addition to respiratory support and other supportive care, use of corticosteroids has shown to improve outcome. Despite the use of steroids, a significant proportion of patients progressively worsen. Adjunct immunomodulators have been studied in addition to steroids in these patients. Here we present a successful use of tofacitinib, a Janus Kinase inhibitor, in conjunction with dexamethasone for a patient with rapid worsening of respiratory status and with high level of serum inflammatory biomarkers.
Subject(s)
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Case report / Prognostic study Limits: Humans Language: English Journal: JNMA J Nepal Med Assoc Year: 2021 Document Type: Article

Similar

MEDLINE
LILACS
LIS
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Case report / Prognostic study Limits: Humans Language: English Journal: JNMA J Nepal Med Assoc Year: 2021 Document Type: Article