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Curcumin and Piperine in COVID-19: A Promising Duo to the Rescue?
Miryan, Mahsa; Soleimani, Davood; Askari, Gholamreza; Jamialahmadi, Tannaz; Guest, Paul C; Bagherniya, Mohammad; Sahebkar, Amirhossein.
  • Miryan M; Student Research Committee, Nutrition Research Center, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Soleimani D; Nutrition Research Center, Student Research Committee, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Askari G; Nutritional Sciences Department, School of Nutritional Sciences and Food Technology, Kermanshah University of Medical Sciences, Kermanshah, Iran.
  • Jamialahmadi T; Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
  • Guest PC; Anesthesia and Critical Care Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
  • Bagherniya M; Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran.
  • Sahebkar A; Department of Food Science and Technology, Quchan Branch, Islamic Azad University, Quchan, Iran.
Adv Exp Med Biol ; 1327: 197-204, 2021.
Article in English | MEDLINE | ID: covidwho-1316249
ABSTRACT
COVID-19 is now pandemic throughout the world, and scientists are searching for effective therapies to prevent or treat the disease. The combination of curcumin and piperine is a potential option for the management of COVID-19 based on several mechanisms including antiviral, anti-inflammatory, immunomodulatory, antifibrotic, and antioxidant effects. Here, we describe the probable mechanism of curcumin-piperine against COVID-19. Administration of curcumin-piperine combination appears as a potential strategy to counterbalance the pathophysiological features of COVID-19 including inflammation. The optimal dose and duration of curcumin-piperine supplementation should be determined in the future.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Curcumin / COVID-19 Limits: Humans Language: English Journal: Adv Exp Med Biol Year: 2021 Document Type: Article Affiliation country: 978-3-030-71697-4_16

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Curcumin / COVID-19 Limits: Humans Language: English Journal: Adv Exp Med Biol Year: 2021 Document Type: Article Affiliation country: 978-3-030-71697-4_16