Your browser doesn't support javascript.
Multisystem inflammatory syndrome in children with COVID-19.
Gottlieb, Michael; Bridwell, Rachel; Ravera, Joseph; Long, Brit.
  • Gottlieb M; Department of Emergency Medicine, Rush University Medical Center, USA. Electronic address: michaelgottliebmd@gmail.com.
  • Bridwell R; Department of Emergency Medicine, Brooke Army Medical Center, USA.
  • Ravera J; Department of Surgery, Division of Emergency Medicine, University of Vermont, USA.
  • Long B; Department of Emergency Medicine, Brooke Army Medical Center, USA.
Am J Emerg Med ; 49: 148-152, 2021 11.
Article in English | MEDLINE | ID: covidwho-1316366
ABSTRACT

BACKGROUND:

Multisystem inflammatory syndrome in children (MIS-C) is a dangerous pediatric complication of COVID-19.

OBJECTIVE:

The purpose of this review article is to provide a summary of the diagnosis and management of MIS-C with a focus on management in the acute care setting.

DISCUSSION:

MIS-C is an inflammatory syndrome which can affect nearly any organ system. The most common symptoms are fever and gastrointestinal symptoms, though neurologic and dermatologic findings are also well-described. The diagnosis includes a combination of clinical and laboratory testing. Patients with MIS-C will often have elevated inflammatory markers and may have an abnormal electrocardiogram or echocardiogram. Initial treatment involves resuscitation with careful assessment for cardiac versus vasodilatory shock using point-of-care ultrasound. Treatment should include intravenous immunoglobulin, anticoagulation, and consideration of corticosteroids. Interleukin-1 and/or interleukin-6 blockade may be considered for refractory cases. Aspirin is recommended if there is thrombocytosis or Kawasaki disease-like features on echocardiogram. Patients will generally require admission to an intensive care unit.

CONCLUSION:

MIS-C is a condition associated with morbidity and mortality that is increasingly recognized as a potential complication in pediatric patients with COVID-19. It is important for emergency clinicians to know how to diagnose and treat this disorder.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Systemic Inflammatory Response Syndrome / COVID-19 Type of study: Diagnostic study / Prognostic study Topics: Long Covid Limits: Adolescent / Child / Child, preschool / Humans / Infant / Infant, Newborn Language: English Journal: Am J Emerg Med Year: 2021 Document Type: Article

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Systemic Inflammatory Response Syndrome / COVID-19 Type of study: Diagnostic study / Prognostic study Topics: Long Covid Limits: Adolescent / Child / Child, preschool / Humans / Infant / Infant, Newborn Language: English Journal: Am J Emerg Med Year: 2021 Document Type: Article