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COVID-19 mRNA vaccines.
Huang, Qingrui; Zeng, Jiawei; Yan, Jinghua.
  • Huang Q; CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
  • Zeng J; CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 101408, China.
  • Yan J; CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 101408, China. Electronic address: yanjh@im.ac.cn.
J Genet Genomics ; 48(2): 107-114, 2021 02 20.
Article in English | MEDLINE | ID: covidwho-1316536
ABSTRACT
The ongoing COVID-19 pandemic and its unprecedented global societal and economic disruptive impact highlight the urgent need for safe and effective vaccines. Taking substantial advantages of versatility and rapid development, two mRNA vaccines against COVID-19 have completed late-stage clinical assessment at an unprecedented speed and reported positive results. In this review, we outline keynotes in mRNA vaccine development, discuss recently published data on COVID-19 mRNA vaccine candidates, focusing on those in clinical trials and analyze future potential challenges.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: RNA, Messenger / Vaccines, Synthetic / COVID-19 Vaccines / SARS-CoV-2 / COVID-19 Type of study: Observational study / Prognostic study Topics: Vaccines Limits: Humans Language: English Journal: J Genet Genomics Year: 2021 Document Type: Article Affiliation country: J.jgg.2021.02.006

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Full text: Available Collection: International databases Database: MEDLINE Main subject: RNA, Messenger / Vaccines, Synthetic / COVID-19 Vaccines / SARS-CoV-2 / COVID-19 Type of study: Observational study / Prognostic study Topics: Vaccines Limits: Humans Language: English Journal: J Genet Genomics Year: 2021 Document Type: Article Affiliation country: J.jgg.2021.02.006