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Tackling Antimicrobial Resistance in the Shadow of COVID-19.
Patel, Ami.
  • Patel A; Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, Pennsylvania, USA.
mBio ; 12(4): e0047321, 2021 08 31.
Article in English | MEDLINE | ID: covidwho-1318003
ABSTRACT
The coronavirus disease 2019 (COVID-19) pandemic is a challenge for ongoing efforts to combat antimicrobial-resistant (AMR) bacterial infections. As we learn more about COVID-19 disease and drug stewardship evolves, there is likely to be a lasting impact of increased use of antimicrobial agents and antibiotics, as well as a lack of consistent access to health care across many populations. Sexually transmitted infections have been underreported during the pandemic and are often caused by some of the most drug-resistant pathogens. In their recent article in mBio, Parzych et al. (E. M. Parzych, S. Gulati, B. Zheng, M. A. Bah, et al., mBio 12e00242-21, 2021, https//doi.org/10.1128/mBio.00242-21) focus on protection against Neisseria gonorrhoeae infection via in vivo delivery of an antigonococcal DNA-encoded antibody that has been modified for increased complement activation. Nucleic acid approaches are highly adaptable and could be tremendously beneficial for personalized strategies to combat AMR pathogens.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Drug Resistance, Multiple, Bacterial / Antimicrobial Stewardship / COVID-19 / Anti-Bacterial Agents Type of study: Prognostic study Limits: Humans Language: English Journal: MBio Year: 2021 Document Type: Article Affiliation country: MBio.00473-21

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Drug Resistance, Multiple, Bacterial / Antimicrobial Stewardship / COVID-19 / Anti-Bacterial Agents Type of study: Prognostic study Limits: Humans Language: English Journal: MBio Year: 2021 Document Type: Article Affiliation country: MBio.00473-21