Your browser doesn't support javascript.
Improved glycaemia during the Covid-19 pandemic lockdown is sustained post-lockdown and during the "Eat Out to Help Out" Government Scheme, in adults with Type 1 diabetes in the United Kingdom.
Avari, Parizad; Unsworth, Rebecca; Rilstone, Siân; Uduku, Chukwuma; Logan, Karen M; Hill, Neil E; Godsland, Ian F; Reddy, Monika; Oliver, Nick.
  • Avari P; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.
  • Unsworth R; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.
  • Rilstone S; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.
  • Uduku C; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.
  • Logan KM; Department of Paediatrics, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom.
  • Hill NE; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.
  • Godsland IF; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.
  • Reddy M; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.
  • Oliver N; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.
PLoS One ; 16(7): e0254951, 2021.
Article in English | MEDLINE | ID: covidwho-1318326
ABSTRACT

AIMS:

The majority of studies report that the Covid-19 pandemic lockdown did not have a detrimental effect on glycaemia. We sought to explore the impact of lockdown on glycaemia and whether this is sustained following easing of restrictions.

METHODS:

Retrospective, observational analysis in adults and children with type 1 diabetes attending a UK specialist centre, using real-time or intermittently scanned continuous glucose monitoring. Data from the following 28-day time periods were collected (i) pre-lockdown; (ii) during lockdown; (iii) immediately after lockdown; and (iv) a month following relaxation of restrictions (coinciding with Government-subsidised restaurant food). Data were analysed for times in glycaemic ranges and are expressed as median (IQR).

RESULTS:

145 adults aged 35.5 (25.8-51.3) years with diabetes duration of 19.0 (7.0-29.0) years on multiple daily injections of insulin (60%) and continuous insulin infusion (40%) were included. In adults, % time in range (70-180mg/dL) increased during lockdown (60.2 (45.2-69.3)%) compared to pre-lockdown (56.7 (43.5-65.3)%; p<0.001). This was maintained in the post-lockdown time periods. Similarly, % time above range (>180mg/dL) reduced in lockdown compared to pre-lockdown (p = 0.01), which was sustained thereafter. In children, no significant changes to glycaemia were observed during lockdown. In multivariable analysis, a greater increase in %TIR 3.9-10mmol/L (70-180mg/dL) during lockdown was associated with higher levels of deprivation (coefficient 4.208, 95% CI 0.588 to 7.828; p = 0.02).

CONCLUSIONS:

Glycaemia in adults improved during lockdown, with people from more deprived areas most likely to benefit. This effect was sustained after easing of restrictions, with government-subsidised restaurant eating having no adverse impact on glycaemia.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: Diabetes Mellitus, Type 1 / COVID-19 Type of study: Observational study / Prognostic study Limits: Adult / Female / Humans / Male Country/Region as subject: Europa Language: English Journal: PLoS One Journal subject: Science / Medicine Year: 2021 Document Type: Article Affiliation country: Journal.pone.0254951

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Diabetes Mellitus, Type 1 / COVID-19 Type of study: Observational study / Prognostic study Limits: Adult / Female / Humans / Male Country/Region as subject: Europa Language: English Journal: PLoS One Journal subject: Science / Medicine Year: 2021 Document Type: Article Affiliation country: Journal.pone.0254951