[Endothelial dysfunction in COVID- 19 and cognitive impairment]. / Endotelial'naya disfunktsiya pri COVID-19 i kognitivnye narusheniya.
Zh Nevrol Psikhiatr Im S S Korsakova
; 121(6): 93-99, 2021.
Article
in Russian
| MEDLINE | ID: covidwho-1318478
ABSTRACT
Endothelial dysfunction is an important mechanism underlying multiple organ and systems failure in COVID-19. The development of endothelial dysfunction in COVID-19 can disrupt organ perfusion and cause a procoagulant state, leading to both macro- and microvascular thrombotic events. Cognitive impairment is a common complication of COVID-19 that develop in acute and delayed periods and is not directly related to the severity of the underlying disease. Treatment of endothelial dysfunction in patients with COVID-19 should take into account the leading pathogenetic factors of its development and with the development of neurological, including cognitive, disorders should include neuroprotective drugs. One of these drugs is actovegin, which has been shown to be effective in improving endothelial function, microcirculation and cognition.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Thrombosis
/
Cognitive Dysfunction
/
COVID-19
Type of study:
Prognostic study
Limits:
Humans
Language:
Russian
Journal:
Zh Nevrol Psikhiatr Im S S Korsakova
Journal subject:
Neurology
/
Psychiatry
Year:
2021
Document Type:
Article
Affiliation country:
Jnevro202112106193
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