Your browser doesn't support javascript.
National Early Warning Score 2 and laboratory predictors correlate with clinical deterioration in hospitalized patients with COVID-19.
Tuncer, Gulsah; Surme, Serkan; Bayramlar, Osman F; Karanalbant, Hatice K; Copur, Betul; Yazla, Meltem; Zerdali, Esra; Nakir, Inci Y; Cinar, Ayse Rk; Buyukyazgan, Ahmet; Balli, Hatice; Kurekci, Yesim; Simsek-Yavuz, Serap; Sonmez, Mehmet M; Sengoz, Gonul; Pehlivanoglu, Filiz.
  • Tuncer G; Department of Infectious Diseases & Clinical Microbiology, Haseki Training & Research Hospital, Istanbul, Turkey.
  • Surme S; Department of Infectious Diseases & Clinical Microbiology, Haseki Training & Research Hospital, Istanbul, Turkey.
  • Bayramlar OF; Department of Public Health, Bakirkoy District Health Directorate, Istanbul, Turkey.
  • Karanalbant HK; Department of Infectious Diseases & Clinical Microbiology, Haseki Training & Research Hospital, Istanbul, Turkey.
  • Copur B; Department of Infectious Diseases & Clinical Microbiology, Haseki Training & Research Hospital, Istanbul, Turkey.
  • Yazla M; Department of Infectious Diseases & Clinical Microbiology, Haseki Training & Research Hospital, Istanbul, Turkey.
  • Zerdali E; Department of Infectious Diseases & Clinical Microbiology, Haseki Training & Research Hospital, Istanbul, Turkey.
  • Nakir IY; Department of Infectious Diseases & Clinical Microbiology, Haseki Training & Research Hospital, Istanbul, Turkey.
  • Cinar AR; Department of Infectious Diseases & Clinical Microbiology, Haseki Training & Research Hospital, Istanbul, Turkey.
  • Buyukyazgan A; Department of Infectious Diseases & Clinical Microbiology, Haseki Training & Research Hospital, Istanbul, Turkey.
  • Balli H; Department of Infectious Diseases & Clinical Microbiology, Haseki Training & Research Hospital, Istanbul, Turkey.
  • Kurekci Y; Department of Infectious Diseases & Clinical Microbiology, Haseki Training & Research Hospital, Istanbul, Turkey.
  • Simsek-Yavuz S; Department of Infectious Diseases & Clinical Microbiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
  • Sonmez MM; Department of Orthopaedic Surgery & Traumatology, Haseki Training & Research Hospital, Istanbul, Turkey.
  • Sengoz G; Department of Infectious Diseases & Clinical Microbiology, Haseki Training & Research Hospital, Istanbul, Turkey.
  • Pehlivanoglu F; Department of Infectious Diseases & Clinical Microbiology, Haseki Training & Research Hospital, Istanbul, Turkey.
Biomark Med ; 15(11): 807-820, 2021 08.
Article in English | MEDLINE | ID: covidwho-1319562
ABSTRACT

Aim:

We aimed to determine the prognostic values of the National Early Warning Score 2 (NEWS2) and laboratory parameters during the first week of COVID-19. Materials &

methods:

All adult patients who were hospitalized for confirmed COVID-19 between 11 March and 11 May 2020 were retrospectively included.

Results:

Overall, 611 patients were included. Our results showed that NEWS2, procalcitonin, neutrophil/lymphocyte ratio and albumin at D0, D3, D5 and D7 were the best predictors for clinical deterioration defined as a composite of ICU admission during hospitalization or in-hospital death. Procalcitonin had the highest odds ratio for clinical deterioration on all days.

Conclusion:

This study provides a list of several laboratory parameters correlated with NEWS2 and potential predictors for clinical deterioration in patients with COVID-19.
Lay abstract The COVID-19 pandemic is a grueling problem worldwide. There is a lack of knowledge about the predictive value of National Early Warning Score 2 (NEWS2) for severe COVID-19 illness. We analyzed the prognostic value of NEWS2 and laboratory parameters during the clinical course of COVID-19. This study provides a list of several laboratory parameters correlated with NEWS2 and potential predictors for intensive care unit admission during hospitalization or in-hospital death.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Procalcitonin / COVID-19 Type of study: Etiology study / Prognostic study / Randomized controlled trials / Risk factors Limits: Humans Language: English Journal: Biomark Med Journal subject: Biochemistry / Medicine Year: 2021 Document Type: Article Affiliation country: Bmm-2021-0061

Full text: Available Collection: International databases Database: MEDLINE Main subject: Procalcitonin / COVID-19 Type of study: Etiology study / Prognostic study / Randomized controlled trials / Risk factors Limits: Humans Language: English Journal: Biomark Med Journal subject: Biochemistry / Medicine Year: 2021 Document Type: Article Affiliation country: Bmm-2021-0061