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Effect of SARS-CoV-2 Infection in Pregnancy on Maternal and Neonatal Outcomes in Africa: An AFREhealth Call for Evidence through Multicountry Research Collaboration
American Journal of Tropical Medicine and Hygiene ; 104(2):461-465, 2021.
Article in English | Africa Wide Information | ID: covidwho-1320717
ABSTRACT
WATERLIT Abstract In the African context, there is a paucity of data on SARS-CoV-2 infection and associated COVID-19 in pregnancy. Given the endemicity of infections such as malaria, HIV, and tuberculosis (TB) in sub-Saharan Africa (SSA), it is important to evaluate coinfections with SARS-CoV-2 and their impact on maternal/infant outcomes. Robust research is critically needed to evaluate the effects of the added burden of COVID-19 in pregnancy, to help develop evidence-based policies toward improving maternal and infant outcomes. In this perspective, we briefly review current knowledge on the clinical features of COVID-19 in pregnancy;the risks of preterm birth and cesarean delivery secondary to comorbid severity;the effects of maternal SARS-CoV-2 infection on the fetus/neonate;and in utero mother-to-child SARS-CoV-2 transmission. We further highlight the need to conduct multicountry surveillance as well as retrospective and prospective cohort studies across SSA. This will enable assessments of SARS-CoV-2 burden among pregnant African women and improve the understanding of the spectrum of COVID-19 manifestations in this population, which may be living with or without HIV, TB, and/or other coinfections/comorbidities. In addition, multicountry studies will allow a better understanding of risk factors and outcomes to be compared across countries and subregions. Such an approach will encourage and strengthen much-needed intra-African, south-to-south multidisciplinary and interprofessional research collaborations. The African Forum for Research and Education in Health's COVID-19 Research Working Group has embarked upon such a collaboration across Western, Central, Eastern and Southern Africa
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Collection: Databases of international organizations Database: Africa Wide Information Type of study: Experimental Studies Language: English Journal: American Journal of Tropical Medicine and Hygiene Year: 2021 Document Type: Article

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Collection: Databases of international organizations Database: Africa Wide Information Type of study: Experimental Studies Language: English Journal: American Journal of Tropical Medicine and Hygiene Year: 2021 Document Type: Article