Diabetes mellitus as a risk factor for SARS-CoV-2 test positivity in Mexico: A propensity score matched study.
Diabetes Res Clin Pract
; 178: 108953, 2021 Aug.
Article
in English
| MEDLINE | ID: covidwho-1322065
ABSTRACT
AIMS:
We sought to investigate whether individuals with diabetes have a higher likelihood of testing positive for SARS-CoV-2, as a proxy for infection risk, than individuals without diabetes.METHODS:
We conducted a cross-sectional study of publicly available data among a Mexican population, totaling 2,314,022 adultsâ¯≥â¯18â¯years who underwent SARS-CoV-2 testing between March 1 and December 20, 2020. We used 11 nearest neighborhood propensity score matching by diabetes status to account for confounding among those with and without diabetes.RESULTS:
In the overall study population, 1,057,779 (45.7%) individuals tested positive for SARS-CoV-2 and 270,486 (11.7%) self-reported diabetes. After propensity score matching, patient characteristics were well-balanced, with 150,487 patients in the diabetes group (mean [SD] age 55.9 [12.7] years; 51.3% women) and 150,487 patients in the no diabetes group (55.5 [13.3] years; 50.3% women). The strictest matching algorithm (11 nearest neighbor) showed that compared to individuals without diabetes, having diabetes was associated with 9.0% higher odds of having a positive SARS-CoV-2 test (OR 1.09 [95% CI 1.08-1.10]).CONCLUSIONS:
Presence of diabetes was associated with higher odds of testing positive for SARS-CoV-2, which could have important implications for risk mitigation efforts for people with diabetes at risk of SARS-CoV-2 infection.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Diabetes Mellitus
/
COVID-19
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
/
Randomized controlled trials
Limits:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
/
Young adult
Country/Region as subject:
Mexico
Language:
English
Journal:
Diabetes Res Clin Pract
Journal subject:
Endocrinology
Year:
2021
Document Type:
Article
Affiliation country:
J.diabres.2021.108953
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