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Guillain Barrè syndrome and myelitis associated with SARS-CoV-2 infection.
Canavero, Isabella; Ravaglia, Sabrina; Valentino, Francesca; Micieli, Giuseppe.
  • Canavero I; Current affiliation: Cerebrovascular Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy; Emergency Neurology Unit, IRCCS Casimiro Mondino Foundation, Pavia, Italy. Electronic address: isabella.canavero@istituto-besta.it.
  • Ravaglia S; Emergency Neurology Unit, IRCCS Casimiro Mondino Foundation, Pavia, Italy.
  • Valentino F; Emergency Neurology Unit, IRCCS Casimiro Mondino Foundation, Pavia, Italy.
  • Micieli G; Emergency Neurology Unit, IRCCS Casimiro Mondino Foundation, Pavia, Italy.
Neurosci Lett ; 759: 136040, 2021 08 10.
Article in English | MEDLINE | ID: covidwho-1322284
Semantic information from SemMedBD (by NLM)
1. COVID-19 COEXISTS_WITH Guillain-Barre Syndrome
Subject
COVID-19
Predicate
COEXISTS_WITH
Object
Guillain-Barre Syndrome
2. COVID-19 COEXISTS_WITH Myelitis
Subject
COVID-19
Predicate
COEXISTS_WITH
Object
Myelitis
3. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
4. Myelitis PROCESS_OF Patients
Subject
Myelitis
Predicate
PROCESS_OF
Object
Patients
5. Paralysed PROCESS_OF Patients
Subject
Paralysed
Predicate
PROCESS_OF
Object
Patients
6. Polyradiculoneuritis PROCESS_OF Patients
Subject
Polyradiculoneuritis
Predicate
PROCESS_OF
Object
Patients
7. COVID-19 COEXISTS_WITH Guillain-Barre Syndrome
Subject
COVID-19
Predicate
COEXISTS_WITH
Object
Guillain-Barre Syndrome
8. COVID-19 COEXISTS_WITH Myelitis
Subject
COVID-19
Predicate
COEXISTS_WITH
Object
Myelitis
9. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
10. Myelitis PROCESS_OF Patients
Subject
Myelitis
Predicate
PROCESS_OF
Object
Patients
11. Paralysed PROCESS_OF Patients
Subject
Paralysed
Predicate
PROCESS_OF
Object
Patients
12. Polyradiculoneuritis PROCESS_OF Patients
Subject
Polyradiculoneuritis
Predicate
PROCESS_OF
Object
Patients
ABSTRACT
Despite a likely underestimation due to the many obstacles of the highly infectious, intensive care setting, increasing clinical reports about COVID-19 patients developing acute paralysis for polyradiculoneuritis or myelitis determine additional impact on the disease course and outcome. Different pathogenic mechanisms have been postulated basing on clinical, laboratory and neuroimaging features, and response to treatments. Here we provide an overview with insights built on the available reports. Besides direct viral pathogenicity, a crucial role seems to be represented by immune-mediated mechanisms, supporting and further characterizing the already hypothesized neurotropic potential of SARS-CoV-2 and implying specific treatments. Proper clinical and instrumental depiction of symptomatic cases, as well as screening for their early recognition is advocated.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Guillain-Barre Syndrome / COVID-19 / Myelitis Type of study: Risk factors Limits: Humans Language: English Journal: Neurosci Lett Year: 2021 Document Type: Article

Full text: Available Collection: International databases Database: MEDLINE Main subject: Guillain-Barre Syndrome / COVID-19 / Myelitis Type of study: Risk factors Limits: Humans Language: English Journal: Neurosci Lett Year: 2021 Document Type: Article