Patients with history of covid-19 had more side effects after the first dose of covid-19 vaccine.
Vaccine
; 39(36): 5087-5090, 2021 08 23.
Article
in English
| MEDLINE | ID: covidwho-1322380
ABSTRACT
INTRODUCTION:
COVID-19 vaccination seems to be the most pertinent pharmacologic public health measure to control the pandemic. Reactogenicity symptoms were frequent in vaccine recipients mostly mild to moderate and commonly reported after the second dose. However, there is a lack of data in patients with a previous diagnosis of Covid-19.METHODS:
We analysed side effects of 311 patients after the first dose of Pfizer-BioNTech COVID-19 vaccine, in a french university hospital. We compared patients with COVID-19 history to naive individuals. All the data collected are based on self-reported, including COVID-19 exposure status.RESULTS:
Overall, 229 (74%) patients reported at least one side effect. Among participants with history of Covid-19, 95% reported at least one adverse event versus 70% in naive patients (p < 0.01). However, symptom intensity was not different between the 2 groups.CONCLUSION:
Vaccine recipients with prior COVID-19 reported more, but no more serious, side effects than naive participants.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Drug-Related Side Effects and Adverse Reactions
/
COVID-19
Type of study:
Experimental Studies
/
Observational study
/
Prognostic study
/
Randomized controlled trials
Topics:
Vaccines
Limits:
Humans
Language:
English
Journal:
Vaccine
Year:
2021
Document Type:
Article
Affiliation country:
J.vaccine.2021.07.047
Similar
MEDLINE
...
LILACS
LIS