Current Use of Ivermectin in Dermatology, Tropical Medicine, and COVID-19: An Update on Pharmacology, Uses, Proven and Varied Proposed Mechanistic Action.

Mathachan, Sinu Rose; Sardana, Kabir; Khurana, Ananta

Mathachan, Sinu Rose; Sardana, Kabir; Khurana, Ananta.

Mathachan SR; Departments of Dermatology, Venereology and Leprosy, ABVIMS and Dr. Ram Manohar Lohia Hospital, New Delhi, India.
Sardana K; Departments of Dermatology, Venereology and Leprosy, ABVIMS and Dr. Ram Manohar Lohia Hospital, New Delhi, India.
Khurana A; Departments of Dermatology, Venereology and Leprosy, ABVIMS and Dr. Ram Manohar Lohia Hospital, New Delhi, India.

Indian Dermatol Online J ; 12(4): 500-514, 2021.

Article in English | MEDLINE | ID: covidwho-1323347

ABSTRACT

ABSTRACT

Ivermectin is a broad-spectrum antiparasitic drug with anti-inflammatory, anti-viral, anti-bacterial, and anti-tumor effects. In this review, we discuss the history, pharmacology, multimodal actions, indications in dermatology and tropical medicine, therapeutic and prophylactic use of ivermectin in COVID-19, safety, adverse effects, special considerations, and drug interactions of ivermectin.

Keywords

Action; COVID-19; cutaneous larva migrans; demodicosis; dermatology; dose; drug interaction; filariasis; ivermectin; malaria; nematodes; onchocerciasis; pediculosis; prophylaxis; rosacea; safety; scabies; side effects; tropical; uses

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Prognostic study Language: English Journal: Indian Dermatol Online J Year: 2021 Document Type: Article Affiliation country: Idoj.idoj_298_21

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