Dysregulated liver function in SARS-CoV-2 infection: Current understanding and perspectives.
World J Gastroenterol
; 27(27): 4358-4370, 2021 Jul 21.
Article
in English
| MEDLINE | ID: covidwho-1328147
ABSTRACT
Since it was first reported in December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has spread rapidly around the world to cause the ongoing pandemic. Although the clinical manifestations of SARS-CoV-2 infection are predominantly in the respiratory system, liver enzyme abnormalities exist in around half of the cases, which indicate liver injury, and raise clinical concern. At present, there is no consensus whether the liver injury is directly caused by viral replication in the liver tissue or indirectly by the systemic inflammatory response. This review aims to summarize the clinical manifestations and to explore the underlying mechanisms of liver dysfunction in patients with SARS-CoV-2 infection.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
SARS-CoV-2
/
COVID-19
Type of study:
Prognostic study
Limits:
Humans
Language:
English
Journal:
World J Gastroenterol
Journal subject:
Gastroenterology
Year:
2021
Document Type:
Article
Affiliation country:
Wjg.v27.i27.4358
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