Your browser doesn't support javascript.
Biological function of furin in viral infections
Zhongguo Bingdubing Zazhi = Chinese Journal of Viral Diseases ; - (3):209, 2021.
Article in English | ProQuest Central | ID: covidwho-1329332
ABSTRACT
Most viruses require their glycoproteins to be hydrolyzed in order to enter host cells.In some cases, the severability of viral glycoproteins is a determinant of their virulence.These viral glycoproteins can be cleaved by one or more proteases in host cells with furin as the common one.Furin further promotes viral infection by identifying specific amino acid sequences in glycoprotein precursors.Morever, furin plays a critical role in the infections of many viruses including human immunodeficiency virus, flavivirus, filamentavirus and coronavirus, and is considered as a promising drug treatment and prevention target.In this review, we summarize the biological background of furin and its hydrolysis function to viral glycoproteins.
Search on Google
Collection: Databases of international organizations Database: ProQuest Central Language: English Journal: Zhongguo Bingdubing Zazhi = Chinese Journal of Viral Diseases Year: 2021 Document Type: Article

Similar

MEDLINE

...
LILACS

LIS

Search on Google
Collection: Databases of international organizations Database: ProQuest Central Language: English Journal: Zhongguo Bingdubing Zazhi = Chinese Journal of Viral Diseases Year: 2021 Document Type: Article