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Guillain-Barré Syndrome Variant Occurring after SARS-CoV-2 Vaccination.
Allen, Christopher Martin; Ramsamy, Shelby; Tarr, Alexander William; Tighe, Patrick Jason; Irving, William Lucien; Tanasescu, Radu; Evans, Jonathan Rhys.
  • Allen CM; Department of Neurology, Nottingham University Hospitals National Health Service Trust, Nottingham, UK.
  • Ramsamy S; School of Medicine, University of Nottingham, Nottingham, UK.
  • Tarr AW; Department of Neurology, Nottingham University Hospitals National Health Service Trust, Nottingham, UK.
  • Tighe PJ; National Institute for Health Research Nottingham Biomedical Research Centre, Nottingham University Hospitals National Health Service Trust, Nottingham, UK.
  • Irving WL; School of Life Sciences, University of Nottingham, Nottingham, UK.
  • Tanasescu R; National Institute for Health Research Nottingham Biomedical Research Centre, Nottingham University Hospitals National Health Service Trust, Nottingham, UK.
  • Evans JR; School of Life Sciences, University of Nottingham, Nottingham, UK.
Ann Neurol ; 90(2): 315-318, 2021 08.
Article in English | MEDLINE | ID: covidwho-1330296
ABSTRACT
Although SARS-CoV-2 vaccines are very safe, we report 4 cases of the bifacial weakness with paresthesias variant of Guillain-Barré syndrome (GBS) occurring within 3 weeks of vaccination with the Oxford-AstraZeneca SARS-CoV-2 vaccine. This rare neurological syndrome has previously been reported in association with SARS-CoV-2 infection itself. Our cases were given either intravenous immunoglobulin, oral steroids, or no treatment. We suggest vigilance for cases of bifacial weakness with paresthesias variant GBS following vaccination for SARS-CoV-2 and that postvaccination surveillance programs ensure robust data capture of this outcome, to assess for causality. ANN NEUROL 2021;90315-318.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Guillain-Barre Syndrome / COVID-19 Vaccines Type of study: Case report / Diagnostic study / Prognostic study Topics: Vaccines / Variants Limits: Adult / Humans / Male / Middle aged / Young adult Language: English Journal: Ann Neurol Year: 2021 Document Type: Article Affiliation country: Ana.26144

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Guillain-Barre Syndrome / COVID-19 Vaccines Type of study: Case report / Diagnostic study / Prognostic study Topics: Vaccines / Variants Limits: Adult / Humans / Male / Middle aged / Young adult Language: English Journal: Ann Neurol Year: 2021 Document Type: Article Affiliation country: Ana.26144