Effects of moderate COVID-19 infection on semen oxidative status and parameters 14 and 120 days after diagnosis.
Reprod Fertil Dev
; 33(12): 683-690, 2021 Oct.
Article
in English
| MEDLINE | ID: covidwho-1331436
ABSTRACT
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus causing coronavirus disease 2019 (COVID-19). Because COVID-19 is a multisystem infection, there are some concerns regarding its possible effects on male fertility. This study aimed to investigate the effects of COVID-19 on semen oxidative status and parameters 14 and 120 days after diagnosis in patients presenting with moderate infection (defined as respiratory symptoms, with or without fever, with Spo2 <93% and >90% and lung involvement <50%). Semen samples were obtained from 20 participants at two time points the first sample on Day 14 and the second on Day 120 after diagnosis. Semen parameters (sperm concentration, motility, morphology, and viability) were evaluated, as were levels of seminal reactive oxygen species (ROS), malondialdehyde (MDA), total antioxidant capacity (TAC) and sperm DNA fragmentation. Semen parameters, including sperm motility and DNA integrity, improved at 120 days after the COVID-19 diagnosis relative to values at 14 days. In addition, ROS and MDA levels were significantly reduced in patients 120 days after infection, and TAC increased at 120 days compared with 14 days (during the acute stage of infection). In conclusion, the present study shows that the detrimental effects of COVID-19 on sperm properties caused by oxidative stress decrease up to Day 120 after diagnosis.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Semen
/
Spermatozoa
/
Oxidative Stress
/
COVID-19
Type of study:
Cohort study
/
Diagnostic study
/
Experimental Studies
/
Observational study
/
Prognostic study
/
Qualitative research
Limits:
Adult
/
Humans
/
Male
/
Middle aged
/
Young adult
Language:
English
Journal:
Reprod Fertil Dev
Journal subject:
Reproductive Medicine
Year:
2021
Document Type:
Article
Affiliation country:
Rd21153
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