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Improving lung compliance by external compression of the chest wall.
Marini, John J; Gattinoni, Luciano.
  • Marini JJ; Pulmonary and Critical Care Medicine, University of Minnesota and Regions Hospital, 640 Jackson St., Minneapolis/St. Paul, Minnesota, 55101, USA. marin002@umn.edu.
  • Gattinoni L; Department of Anesthesiology, Intensive Care and Emergency Medicine, Medical University of Göttingen, Göttingen, Germany.
Crit Care ; 25(1): 264, 2021 07 28.
Article in English | MEDLINE | ID: covidwho-1331951
ABSTRACT
As exemplified by prone positioning, regional variations of lung and chest wall properties provide possibilities for modifying transpulmonary pressures and suggest that clinical interventions related to the judicious application of external pressure may yield benefit. Recent observations made in late-phase patients with severe ARDS caused by COVID-19 (C-ARDS) have revealed unexpected mechanical responses to local chest wall compressions over the sternum and abdomen in the supine position that challenge the clinician's assumptions and conventional bedside approaches to lung protection. These findings appear to open avenues for mechanism-defining research investigation with possible therapeutic implications for all forms and stages of ARDS.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Lung Compliance / Prone Position / COVID-19 Type of study: Observational study / Prognostic study Limits: Humans Language: English Journal: Crit Care Year: 2021 Document Type: Article Affiliation country: S13054-021-03700-8

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Lung Compliance / Prone Position / COVID-19 Type of study: Observational study / Prognostic study Limits: Humans Language: English Journal: Crit Care Year: 2021 Document Type: Article Affiliation country: S13054-021-03700-8