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Extremely Preterm Infant Admissions Within the SafeBoosC-III Consortium During the COVID-19 Lockdown.
Rasmussen, Marie Isabel; Hansen, Mathias Lühr; Pichler, Gerhard; Dempsey, Eugene; Pellicer, Adelina; El-Khuffash, Afif; A, Shashidhar; Piris-Borregas, Salvador; Alsina, Miguel; Cetinkaya, Merih; Chalak, Lina; Özkan, Hilal; Baserga, Mariana; Sirc, Jan; Fuchs, Hans; Ergenekon, Ebru; Arruza, Luis; Mathur, Amit; Stocker, Martin; Otero Vaccarello, Olalla; Szczapa, Tomasz; Sarafidis, Kosmas; Królak-Olejnik, Barbara; Memisoglu, Asli; Reigstad, Hallvard; Rafinska-Wazny, Elzbieta; Hatzidaki, Eleftheria; Peng, Zhang; Gkentzi, Despoina; Viellevoye, Renaud; De Buyst, Julie; Mastretta, Emmanuele; Wang, Ping; Hahn, Gitte Holst; Bender, Lars; Cornette, Luc; Tkaczyk, Jakub; Del Rio, Ruth; Fumagalli, Monica; Papathoma, Evangelia; Wilinska, Maria; Naulaers, Gunnar; Sadowska-Krawczenko, Iwona; Lecart, Chantal; Couce, María Luz; Fredly, Siv; Heuchan, Anne Marie; Karen, Tanja; Greisen, Gorm.
  • Rasmussen MI; Department of Neonatology, Rigshospitalet, Copenhagen, Denmark.
  • Hansen ML; Department of Neonatology, Rigshospitalet, Copenhagen, Denmark.
  • Pichler G; Department of Pediatrics, Medical University of Graz, Graz, Austria.
  • Dempsey E; Infant Centre and Department of Paediatrics and Child Health, University College Cork, Cork, Ireland.
  • Pellicer A; Department of Neonatology, La Paz University Hospital, Madrid, Spain.
  • El-Khuffash A; Department of Pediatrics, The Royal College of Surgeons in Ireland, Dublin, Ireland.
  • A S; St. Johns Medical College Hospital, Bengaluru, India.
  • Piris-Borregas S; Department of Neonatology, 12 Octubre University Hospital, Madrid, Spain.
  • Alsina M; Neonatology Department, Hospital Clínic-Maternintat, Barcelona, Spain.
  • Cetinkaya M; Department of Neonatology, Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey.
  • Chalak L; Division of Pediatrics - Neonatal-Perinatal, University of Texas (UT) Southwestern, Dallas, TX, United States.
  • Özkan H; Division of Neonatology, Department of Pediatrics, Uludag University Medical Faculty, Uludag, Turkey.
  • Baserga M; Division of Neonatology, Department of Pediatrics, University of Utah, Salt Lake City, UT, United States.
  • Sirc J; Third Faculty of Medicine, Institute for the Care of the Mother and Child, Charles University, Prague, Czechia.
  • Fuchs H; Center for Pediatrics, Department of Neonatology, Medical Center, University of Freiburg, Freiburg, Germany.
  • Ergenekon E; Department of Neonatology, Gazi University Hospital, Ankara, Turkey.
  • Arruza L; Division of Neonatology, Instituto del Niño y del Adolescente, Hospital Clinico San Carlos-Health Research Institute San Carlos (IdISSC), Madrid, Spain.
  • Mathur A; Department of Neonatal-Perinatal Medicine, Saint Louis University School of Medicine, St. Louis, MO, United States.
  • Stocker M; Neonatal and Pediatric Intensive Care Unit, Children's Hospital Lucerne, Lucerne, Switzerland.
  • Otero Vaccarello O; Department of Neonatology, Hospital Universitario de Tarragona Juan XXIII, Tarragona, Spain.
  • Szczapa T; Department of Neonatology, Neonatal Biophysical Monitoring and Cardiopulmonary Therapies Research Unit, Poznan University of Medical Sciences, Poznan, Poland.
  • Sarafidis K; First Department of Neonatology, Aristotle University, Hippokrateion General Hospital, Thessaloniki, Greece.
  • Królak-Olejnik B; Department of Neonatology, Wroclaw Medical University, Wroclaw, Poland.
  • Memisoglu A; Department of Neonatology, Marmara University Pendik Training and Research Hospital, Istanbul, Turkey.
  • Reigstad H; Department of Neonatology, Haukeland University Hospital, Bergen, Norway.
  • Rafinska-Wazny E; Department of Neonatology, Centrum Medyczne "Ujastek", Krakow, Poland.
  • Hatzidaki E; Department of Neonatology and Neonatal Intensive Care Unit (NICU), University Hospital of Heraklion, Crete, Greece.
  • Peng Z; Department of Neonatology, Children's Hospital of Fudan University, Shanghai, China.
  • Gkentzi D; Neonatal Intensive Care Unit (NICU), Department of Pediatrics, Patras Medical School, Patras, Greece.
  • Viellevoye R; Neonatal Intensive Care Unit, Department of Pediatrics, University of Liege, Liege, Belgium.
  • De Buyst J; Neonatal Intensive Care Unit (NICU), Tivoli Hospital, La Louviere, Belgium.
  • Mastretta E; S.C. Neonatologia - Pres Osp S. Anna - Citta della Salute e della Scienza di Torino, Torino, Italy.
  • Wang P; Department of Neonatology, Guangzhou Women and Children's Medical Center, Guangzhou, China.
  • Hahn GH; Department of Neonatology, Rigshospitalet, Copenhagen, Denmark.
  • Bender L; Department of Neonatology, Aalborg University Hospital, Aalborg, Denmark.
  • Cornette L; Department of Neonatology, AZ St-Jan Bruges, Bruges, Belgium.
  • Tkaczyk J; Department of Neonatology, University Hospital Motol, Prague, Czechia.
  • Del Rio R; Department of Neonatology, Hospital Sant Joan de Déu, Barcelona, Spain.
  • Fumagalli M; Department of Neonatology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Milan, Milan, Italy.
  • Papathoma E; Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
  • Wilinska M; Neonatal Intensive Care Unit, "Alexandra" University and State Maternity Hospital, Athens, Greece.
  • Naulaers G; Neonatology Department, Centre of Postgraduate Medical Education, Warsaw, Poland.
  • Sadowska-Krawczenko I; Department of Neonatology, University Hospital Leuven, Leuven, Belgium.
  • Lecart C; Department of Neonatology, Collegium Medicum in Bydgoszcz Nicolaus Copernicus University, Torun, Poland.
  • Couce ML; Department of Neonatology, Grand Hôpital de Charleroi (GHdC), Charleroi, Belgium.
  • Fredly S; Neonatology Department, University Clinical Hospital of Santiago de Compostela, Health Research Institute of Santiago de Compostela, Santiago, Spain.
  • Heuchan AM; Department of Neonatology, Oslo University Hospital, Oslo, Norway.
  • Karen T; Department of Neonatology, Royal Hospital for Children, Glasgow, United Kingdom.
  • Greisen G; Department of Neonatology, University Hospital Zurich, Zurich, Switzerland.
Front Pediatr ; 9: 647880, 2021.
Article in English | MEDLINE | ID: covidwho-1332132
Preprint
This scientific journal article is probably based on a previously available preprint. It has been identified through a machine matching algorithm, human confirmation is still pending.
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ABSTRACT

Objective:

To evaluate if the number of admitted extremely preterm (EP) infants (born before 28 weeks of gestational age) differed in the neonatal intensive care units (NICUs) of the SafeBoosC-III consortium during the global lockdown when compared to the corresponding time period in 2019.

Design:

This is a retrospective, observational study. Forty-six out of 79 NICUs (58%) from 17 countries participated. Principal investigators were asked to report the following information (1) Total number of EP infant admissions to their NICU in the 3 months where the lockdown restrictions were most rigorous during the first phase of the COVID-19 pandemic, (2) Similar EP infant admissions in the corresponding 3 months of 2019, (3) the level of local restrictions during the lockdown period, and (4) the local impact of the COVID-19 lockdown on the everyday life of a pregnant woman.

Results:

The number of EP infant admissions during the first wave of the COVID-19 pandemic was 428 compared to 457 in the corresponding 3 months in 2019 (-6.6%, 95% CI -18.2 to +7.1%, p = 0.33). There were no statistically significant differences within individual geographic regions and no significant association between the level of lockdown restrictions and difference in the number of EP infant admissions. A post-hoc analysis based on data from the 46 NICUs found a decrease of 10.3%in the total number of NICU admissions (n = 7,499 in 2020 vs. n = 8,362 in 2019).

Conclusion:

This ad hoc study did not confirm previous reports of a major reduction in the number of extremely pretermbirths during the first phase of the COVID-19 pandemic. Clinical Trial Registration ClinicalTrial.gov, identifier NCT04527601 (registered August 26, 2020), https//clinicaltrials.gov/ct2/show/NCT04527601.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Language: English Journal: Front Pediatr Year: 2021 Document Type: Article Affiliation country: Fped.2021.647880

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Language: English Journal: Front Pediatr Year: 2021 Document Type: Article Affiliation country: Fped.2021.647880