The role of essential organ-based comorbidities in the prognosis of COVID-19 infection patients.
Expert Rev Respir Med
; 14(8): 835-838, 2020 08.
Article
in English
| MEDLINE | ID: covidwho-133651
ABSTRACT
OBJECTIVES:
To assess the role of essential organ-based comorbidities in the prognosis of COVID-19 patients.METHODS:
All consecutive patients diagnosed with COVID-19 admitted to the Zhongnan Hospital of Wuhan University from 11 January to 16 March 2020 were enrolled in this retrospective cohort study.RESULTS:
A total of 212 COVID-19 patients were included. COVID-19 patients with heart, liver and kidneycomorbidity, compared to patients without related comorbidities, were more likely to have cardiac injuries [9.1%(3/33) vs 2.2%(4/179), P = 0.043], liver injuries [13.0%(3/23) vs 3.2%(6/189), P = 0.027], kidney injury [54.5%(6/11) vs 2.0%(4/201), P < 0.001], and higher risk of mortality [Heart-comorbidity 6.1%(2/33) vs 0.6%(1/179), P = 0.014; Liver-comorbidity 8.7%(2/23) vs 0.5%(1/189), P = 0.002; Kidney-comorbidity 27.3%(3/11) vs 1.0%(2/201), P < 0.001. Mortality was higher in patients with more severe Grade of organ injuries [Heart-injury P = 0.044; Liver-injury P = 0.020; Kidney-injury P = 0.030].CONCLUSION:
Male, older, co-existing of heart, liver, and kidney comorbidities, especially those with severe Grade organ injuries, had a poor prognosis after SARS-CoV-2 infection.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia, Viral
/
Comorbidity
/
Coronavirus Infections
/
Betacoronavirus
Type of study:
Cohort study
/
Diagnostic study
/
Observational study
/
Prognostic study
Topics:
Long Covid
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
English
Journal:
Expert Rev Respir Med
Year:
2020
Document Type:
Article
Affiliation country:
17476348.2020.1761791
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