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Aspergillus Polymerase Chain Reaction-An Update on Technical Recommendations, Clinical Applications, and Justification for Inclusion in the Second Revision of the EORTC/MSGERC Definitions of Invasive Fungal Disease.
White, P Lewis; Bretagne, Stephane; Caliendo, Angela M; Loeffler, Juergen; Patterson, Thomas F; Slavin, Monica; Wingard, John R.
  • White PL; Public Health Wales Mycology Reference Laboratory, Cardiff, United Kingdom.
  • Bretagne S; Mycology Laboratory, Saint Louis Hospital, Paris and Université de Paris, France.
  • Caliendo AM; Department of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
  • Loeffler J; Department of Molecular Biology and Infection, University Hospital Wuerzburg, Medical Hospital II, Wuerzburg, Germany.
  • Patterson TF; Department of Medicine, University of Texas Health San Antonio and the South Texas Veterans Health Care System, San Antonio, Texas, USA.
  • Slavin M; National Centre for Infections in Cancer, Sir Peter MacCallum Department of Medical Oncology, University of Melbourne, Melbourne, Australia.
  • Wingard JR; Department of Medicine, University of Florida College of Medicine, Gainesville, Florida, USA.
Clin Infect Dis ; 72(Suppl 2): S95-S101, 2021 03 12.
Article in English | MEDLINE | ID: covidwho-1338678
ABSTRACT
Aspergillus polymerase chain reaction testing of blood and respiratory samples has recently been included in the second revision of the EORTC/MSGERC definitions for classifying invasive fungal disease. This is a result of considerable efforts to standardize methodology, the availability of commercial assays and external quality control programs, and additional clinical validation. This supporting article provides both clinical and technical justifications for its inclusion while also summarizing recent advances and likely future developments in the molecular diagnosis of invasive aspergillosis.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Aspergillosis / Invasive Fungal Infections Type of study: Diagnostic study / Prognostic study Limits: Humans Language: English Journal: Clin Infect Dis Journal subject: Communicable Diseases Year: 2021 Document Type: Article Affiliation country: Cid

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Aspergillosis / Invasive Fungal Infections Type of study: Diagnostic study / Prognostic study Limits: Humans Language: English Journal: Clin Infect Dis Journal subject: Communicable Diseases Year: 2021 Document Type: Article Affiliation country: Cid