Your browser doesn't support javascript.
Clinical outcomes of COVID-19 amongst HIV patients: a systematic literature review.
Massarvva, Thomas.
  • Massarvva T; Department of Primary Care and Population Health, University of Nicosia Medical School, Nicosia, Cyprus.
Epidemiol Health ; 43: e2021036, 2021.
Article in English | MEDLINE | ID: covidwho-1339664
ABSTRACT

OBJECTIVES:

The global pandemic coronavirus disease 2019 (COVID-19) emerged in the city of Wuhan, China around December 2019. Since then, the virus has caused severe morbidity and mortality worldwide and has put pressure on the global medical system. Still, there are limited data regarding the clinical impact of COVID-19 on people living with human immunodeficiency virus (HIV). The primary aim of this study was, therefore, to systematically review up-to-date studies reporting the clinical outcomes of COVID-19 amongst HIV patients.

METHODS:

A thorough literature search was carried out using MEDLINE, Embase, Scopus, and the Cochrane Library Databases in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines.

RESULTS:

A total of 22 studies were identified. Amongst 730 HIV/COVID-19-coinfected patients, 79.4% were males, the median age was 51.5 years, and the number of reported patients receiving antiretroviral drugs was 708 (97.2%). Most coinfected patients had mild to moderate symptoms, including cough (37.7%), fever (37.5%), and dyspnoea (24.7%). Among pre-existing comorbidities, hypertension (26.3%) was the most prevalent in HIV/COVID-19 coinfected patients, and 87% of coinfected patients recovered.

CONCLUSIONS:

Based on the existing data in this systematic literature review, HIV patients with pre-existing comorbidities, obesity, and older age should be considered as a high-risk group for COVID-19. Furthermore, coinfected patients appear to have marginally comparable clinical outcomes with the general population. The study's findings highlight the need for further investigation to elucidate the impact of COVID-19 infection on HIV patients.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: HIV Infections / Anti-Retroviral Agents / Coinfection / COVID-19 Type of study: Diagnostic study / Prognostic study / Reviews / Systematic review/Meta Analysis Topics: Long Covid Limits: Humans Country/Region as subject: Asia Language: English Journal: Epidemiol Health Year: 2021 Document Type: Article Affiliation country: Epih.e2021036

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: HIV Infections / Anti-Retroviral Agents / Coinfection / COVID-19 Type of study: Diagnostic study / Prognostic study / Reviews / Systematic review/Meta Analysis Topics: Long Covid Limits: Humans Country/Region as subject: Asia Language: English Journal: Epidemiol Health Year: 2021 Document Type: Article Affiliation country: Epih.e2021036