Interleukin 6-blockade treatment for severe COVID-19 in two patients with multiple myeloma.

Chaidos, Aristeidis; Katsarou, Alexia; Mustafa, Chira; Milojkovic, Dragana; Karadimitris, Anastasios

Chaidos, Aristeidis; Katsarou, Alexia; Mustafa, Chira; Milojkovic, Dragana; Karadimitris, Anastasios.

Chaidos A; Centre for Haematology, Department of Immunology & Inflammation, Hugh and Josseline Langmuir Centre for Myeloma Research, Imperial College, London, UK.
Katsarou A; Department of Haematology, Imperial College Healthcare NHS Trust, Hammersmith Hospital, London, UK.
Mustafa C; Centre for Haematology, Department of Immunology & Inflammation, Hugh and Josseline Langmuir Centre for Myeloma Research, Imperial College, London, UK.
Milojkovic D; Department of Haematology, Imperial College Healthcare NHS Trust, Hammersmith Hospital, London, UK.
Karadimitris A; Centre for Haematology, Department of Immunology & Inflammation, Hugh and Josseline Langmuir Centre for Myeloma Research, Imperial College, London, UK.

Br J Haematol ; 190(1): e9-e11, 2020 Jul.

Article in English | MEDLINE | ID: covidwho-1343824

Subject(s)

Antibodies, Monoclonal, Humanized/administration & dosage; Betacoronavirus; Coronavirus Infections/drug therapy; Interleukin-6/antagonists & inhibitors; Multiple Myeloma; Neoplasm Proteins/administration & dosage; Pneumonia, Viral/drug therapy; Aged; COVID-19; Humans; Male; Middle Aged; Multiple Myeloma/drug therapy; Multiple Myeloma/virology; Pandemics; SARS-CoV-2; Severity of Illness Index

Keywords

COVID-19; cytokine release syndrome; interleukin-6; myeloma; tocilizumab

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Interleukin-6 / Coronavirus Infections / Antibodies, Monoclonal, Humanized / Betacoronavirus / Multiple Myeloma / Neoplasm Proteins Type of study: Prognostic study Limits: Aged / Humans / Male / Middle aged Language: English Journal: Br J Haematol Year: 2020 Document Type: Article Affiliation country: Bjh.16787

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