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Adjunctive corticosteroid treatment for organizing pneumonia in COVID-19 patients with persistent respiratory failure.
Segala, Francesco Vladimiro; Sgalla, Giacomo; Salvati, Federica; Berardini, Ludovica; Negri, Marcantonio; Nardella, Elisabetta; Potenza, Annalisa; Murri, Rita; Fantoni, Massimo.
  • Segala FV; Infectious Diseases Unit, Catholic University of the Sacred Heart, Rome, Italy. Electronic address: fvsegala@gmail.com.
  • Sgalla G; Unità Operativa Complessa di Pneumologia, Fondazione Policlinico A. Gemelli IRCCS, Rome, Italy.
  • Salvati F; Infectious Diseases Unit, Catholic University of the Sacred Heart, Rome, Italy.
  • Berardini L; Unità Operativa Complessa di Pneumologia, Fondazione Policlinico A. Gemelli IRCCS, Rome, Italy.
  • Negri M; Istituto di Medicina Interna e Gastroenterologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
  • Nardella E; Istituto di Medicina Interna e Gastroenterologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
  • Potenza A; Istituto di Medicina Interna e Gastroenterologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
  • Murri R; Division of Infectious Diseases, Department of Laboratory Sciences and Infectious Diseases, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
  • Fantoni M; Division of Infectious Diseases, Department of Laboratory Sciences and Infectious Diseases, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Respir Med ; 187: 106571, 2021 10.
Article in English | MEDLINE | ID: covidwho-1347816
ABSTRACT
Since the beginning of COVID-19 pandemic, clinical, radiological and histopathological features consistent with viral-induced organizing pneumonia (OP) have been reported as hallmark characteristics of the disease. Here, we describe the case of ten patients with severe COVID-19 pneumonia treated with methylprednisolone 1mg/kg for showing clinical and radiological features suggestive of OP at least 20 days after symptom onset and despite standard treatment for COVID-19.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Respiratory Insufficiency / Dexamethasone / Methylprednisolone / COVID-19 / Glucocorticoids Type of study: Diagnostic study / Prognostic study Topics: Long Covid Limits: Aged / Female / Humans / Male Language: English Journal: Respir Med Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Respiratory Insufficiency / Dexamethasone / Methylprednisolone / COVID-19 / Glucocorticoids Type of study: Diagnostic study / Prognostic study Topics: Long Covid Limits: Aged / Female / Humans / Male Language: English Journal: Respir Med Year: 2021 Document Type: Article