Low morbidity in Danish patients with common variable immunodeficiency disorder infected with severe acute respiratory syndrome coronavirus 2.
Infect Dis (Lond)
; 53(12): 953-958, 2021.
Article
in English
| MEDLINE | ID: covidwho-1348042
ABSTRACT
BACKGROUND:
Manifestations and outcomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are not well documented in patients with common variable immunodeficiency disorder (CVID).METHODS:
A Danish nationwide retrospective clinician-reported survey.RESULTS:
Eleven patients with CVID and SARS-CoV-2 infection were identified. The median age was 50 years (range 22-72). All were on immunoglobulin replacement therapy. Eight patients had other pre-existing co-morbidities. Three patients were asymptomatic during the SARS-CoV-2 infection while seven developed mild coronavirus disease 2019 (COVID-19). One patient had more severe disease with hypoxia and required oxygen therapy. This patient had multiple co-morbidities including well known risk factors for severe COVID-19. All patients recovered.CONCLUSIONS:
The results suggest that CVID may not be a risk factor for severe COVID-19. However, further monitoring of this immunodeficient population is needed to confirm our observation.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Common Variable Immunodeficiency
/
COVID-19
Type of study:
Observational study
/
Prognostic study
Topics:
Long Covid
Limits:
Adult
/
Aged
/
Humans
/
Middle aged
/
Young adult
Country/Region as subject:
Europa
Language:
English
Journal:
Infect Dis (Lond)
Year:
2021
Document Type:
Article
Affiliation country:
23744235.2021.1957144
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