Cluster of Oseltamivir-Resistant and Hemagglutinin Antigenically Drifted Influenza A(H1N1)pdm09 Viruses, Texas, USA, January 2020.

Mohan, Teena; Nguyen, Ha T; Kniss, Krista; Mishin, Vasiliy P; Merced-Morales, Angiezel A; Laplante, Jennifer; St George, Kirsten; Blevins, Patricia; Chesnokov, Anton; De La Cruz, Juan A; Kondor, Rebecca; Wentworth, David E; Gubareva, Larisa V

Mohan, Teena; Nguyen, Ha T; Kniss, Krista; Mishin, Vasiliy P; Merced-Morales, Angiezel A; Laplante, Jennifer; St George, Kirsten; Blevins, Patricia; Chesnokov, Anton; De La Cruz, Juan A; Kondor, Rebecca; Wentworth, David E; Gubareva, Larisa V.

Emerg Infect Dis ; 27(7): 1953-1957, 2021 07.

Article in English | MEDLINE | ID: covidwho-1348448

ABSTRACT

ABSTRACT

Four cases of oseltamivir-resistant influenza A(H1N1)pdm09 virus infection were detected among inhabitants of a border detention center in Texas, USA. Hemagglutinin of these viruses belongs to 6B.1A5A-156K subclade, which may enable viral escape from preexisting immunity. Our finding highlights the necessity to monitor both drug resistance and antigenic drift of circulating viruses.

Subject(s)

Influenza A Virus, H1N1 Subtype; Influenza, Human; Antiviral Agents/therapeutic use; Drug Resistance, Viral; Hemagglutinins; Humans; Influenza, Human/drug therapy; Neuraminidase; Oseltamivir/therapeutic use; Texas; Viral Proteins

Keywords

Texas; United States; antigenic drift; antimicrobial resistance; drug resistance; influenza; influenza A(H1N1); neuraminidase inhibitor; transmission; viruses

Fulltext

XML

PubMed Links

Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: Influenza, Human / Influenza A Virus, H1N1 Subtype Limits: Humans Country/Region as subject: North America Language: English Journal: Emerg Infect Dis Journal subject: Communicable Diseases Year: 2021 Document Type: Article

Similar

MEDLINE

LILACS

LIS

Fulltext

XML

PubMed Links

Search on Google