Risk Factors for Death Among Hospitalized Patients Aged 21-64 Years Diagnosed with COVID-19-New York City, March 13-April 9, 2020.
J Racial Ethn Health Disparities
; 9(4): 1584-1599, 2022 08.
Article
in English
| MEDLINE | ID: covidwho-1349374
ABSTRACT
BACKGROUND:
COVID-19 mortality studies have primarily focused on persons aged ≥ 65 years; less is known about decedents aged <65 years.METHODS:
We conducted a case-control study among NYC residents aged 21-64 years hospitalized with COVID-19 diagnosed March 13-April 9, 2020, to determine risk factors for death. Case-patients (n=343) were hospitalized decedents with COVID-19 and control-patients (n=686) were discharged from hospitalization with COVID-19 and matched 21 to case-patients on age and residential neighborhood. Conditional logistic regression models were adjusted for patient sex, insurance status, and marital status. Matched adjusted odds ratios (aORs) were calculated for selected underlying conditions, combinations of conditions, and race/ethnic group.RESULTS:
Median age of both case-patients and control-patients was 56 years (range 23-64 years). Having ≥ 1 selected underlying condition increased odds of death 4.45-fold (95% CI 2.33-8.49). Patients with diabetes; morbid obesity; heart, kidney, or lung disease; cancer; neurologic/neurodevelopmental conditions; mental health conditions; or HIV had significantly increased odds of death. Compared with having neither condition, having both diabetes and obesity or diabetes and heart disease was associated with approximately threefold odds of death. Five select underlying conditions were more prevalent among non-Hispanic Black control-patients than among control-patients of other races/ethnicities. CONCLUSIONS AND RELEVANCE Selected underlying conditions were risk factors for death, and most prevalent among racial/ethnic minorities. Social services; health care resources, including vaccination; and tailored public health messaging are important for COVID-19 prevention. Strengthening these strategies for racial/ethnic minority groups could minimize COVID-19 racial/ethnic disparities.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
COVID-19
Type of study:
Experimental Studies
/
Observational study
/
Prognostic study
/
Randomized controlled trials
Topics:
Vaccines
Limits:
Adult
/
Humans
/
Middle aged
/
Young adult
Country/Region as subject:
North America
Language:
English
Journal:
J Racial Ethn Health Disparities
Year:
2022
Document Type:
Article
Affiliation country:
S40615-021-01098-1
Similar
MEDLINE
...
LILACS
LIS