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Background rates of all-cause mortality, hospitalizations, and emergency department visits among nursing home residents in Ontario, Canada to inform COVID-19 vaccine safety assessments.
Sundaram, Maria; Nasreen, Sharifa; Calzavara, Andrew; He, Siyi; Chung, Hannah; Bronskill, Susan E; Buchan, Sarah A; Tadrous, Mina; Tanuseputro, Peter; Wilson, Kumanan; Wilson, Sarah; Kwong, Jeffrey C.
  • Sundaram M; ICES, Toronto, ON, Canada; Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
  • Nasreen S; ICES, Toronto, ON, Canada; Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
  • Calzavara A; ICES, Toronto, ON, Canada.
  • He S; ICES, Toronto, ON, Canada.
  • Chung H; ICES, Toronto, ON, Canada.
  • Bronskill SE; ICES, Toronto, ON, Canada; Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada; Women's College Research Institute, Toronto, ON, Canada.
  • Buchan SA; ICES, Toronto, ON, Canada; Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada; Public Health Ontario, ON, Canada.
  • Tadrous M; ICES, Toronto, ON, Canada; Women's College Research Institute, Toronto, ON, Canada; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada.
  • Tanuseputro P; ICES, Toronto, ON, Canada; Department of Medicine, University of Ottawa and Bruyere and Ottawa Hospital Research Institutes, Ottawa, ON, Canada.
  • Wilson K; Department of Medicine, University of Ottawa and Bruyere and Ottawa Hospital Research Institutes, Ottawa, ON, Canada.
  • Wilson S; ICES, Toronto, ON, Canada; Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada; Public Health Ontario, ON, Canada.
  • Kwong JC; ICES, Toronto, ON, Canada; Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada; Public Health Ontario, ON, Canada; Department of Family and Community Medicine, University of Toronto, Toronto, ON, Canada; University Health Network, Toronto, ON, Canada. Electronic address: j
Vaccine ; 39(37): 5265-5270, 2021 08 31.
Article in English | MEDLINE | ID: covidwho-1349600
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ABSTRACT

BACKGROUND:

Nursing home (NH) residents are prioritized for COVID-19 vaccination. We report monthly mortality, hospitalizations, and emergency department (ED) visit incidence rates (IRs) during 2010-2020 to provide context for COVID-19 vaccine safety assessments.

METHODS:

We observed outcomes among all NH residents in Ontario using administrative databases. IRs were calculated by month, sex, and age group. Comparisons between months were assessed using one-sample t-tests; comparisons by age and sex were assessed using chi-squared tests.

RESULTS:

From 2010 to 2019, there were 83,453 (SD 652.4) NH residents per month, with an average of 2.3 (SD 0.28) deaths, 3.1 (SD 0.16) hospitalizations, and 3.6 (SD 0.17) ED visits per 100 residents per month. From March to December 2020, mortality IRs were increased, but hospitalization and ED visit IRs were reduced (p < 0.05).

CONCLUSION:

We identified consistent monthly mortality, hospitalization, and ED visit IRs during 2010-2019. Marked differences in these rates were observed during 2020, coinciding with the COVID-19 pandemic.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Vaccines / COVID-19 / Nursing Homes Type of study: Observational study Topics: Vaccines Limits: Humans Country/Region as subject: North America Language: English Journal: Vaccine Year: 2021 Document Type: Article Affiliation country: J.vaccine.2021.07.060

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Vaccines / COVID-19 / Nursing Homes Type of study: Observational study Topics: Vaccines Limits: Humans Country/Region as subject: North America Language: English Journal: Vaccine Year: 2021 Document Type: Article Affiliation country: J.vaccine.2021.07.060