Analysis of prognostic factors of patients with corona virus disease 2019 in Hefei, China

ABSTRACT

Objective To explore the relationship of prognosis of Corona Virus Disease 2019 (COVID-19) with age and inflammation. Methods The clinical data of 72 patients with COVID-19 in Hefei were collected. The levels of serum C-reactive protein (CRP), interleukin-6 (IL-6), procalcitonin (PCT), erythrocyte sedimentation rate (ESR) were measured. The data was stratified and analyzed according to age, gender and severity of the disease. Results Among the elderly patients with COVID- 19, the proportion of the patients with basic diseases and severe disease was significantly higher, and the proportion of healers was significantly lower than that of other age groups (P<0.05). The levels of IL-6 and CRP in the elderly patients with COVID-19 were significantly higher than those in other age groups (P<0.05) . The levels of IL-6 and CRP in the severe patients were significantly higher than those in the mild patients (P< 0.05) . Conclusions Age and inflammation may increase the patients' susceptibility to the new coronavirus, and also adversely affect the patients' prognosis and outcome.