Is There a Role for Cellular Therapy in Chronic Lymphocytic Leukemia?
Cancer J
; 27(4): 297-305, 2021.
Article
in English
| MEDLINE | ID: covidwho-1354351
ABSTRACT
ABSTRACT Despite multiple advances in the treatment landscape of chronic lymphocytic leukemia (CLL) during recent years, cellular therapies, such as allogeneic hematopoietic cell transplantation and chimeric antigen-engineered T cells, represent valuable therapeutic options for patients with multiply relapsed or poor-risk disease. This brief overview will summarize current results of cellular therapies in CLL including Richter transformation, suggest an indication algorithm and strategies for performing cellular therapies in these conditions, and discuss the impact of COVID-19 (coronavirus disease 2019) on allogeneic hematopoietic cell transplantation and chimeric antigen-engineered T cells in CLL.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Leukemia, Lymphocytic, Chronic, B-Cell
/
Cell- and Tissue-Based Therapy
Type of study:
Prognostic study
Limits:
Humans
Language:
English
Journal:
Cancer J
Journal subject:
Neoplasms
Year:
2021
Document Type:
Article
Affiliation country:
Ppo.0000000000000532
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