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Transient acetylcholine receptor-related myasthenia gravis, post multisystem inflammatory syndrome in children (MIS-C) temporally associated with COVID-19 infection.
Essajee, Farida; Lishman, Juanita; Solomons, Regan; Abraham, Deepthi Raju; Goussard, Pierre; Van Toorn, Ronald.
  • Essajee F; Pediatrics and Child Health, Stellenbosch University Faculty of Medicine and Health Sciences, Cape Town, South Africa.
  • Lishman J; Pediatrics and Child Health, Stellenbosch University Faculty of Medicine and Health Sciences, Cape Town, South Africa.
  • Solomons R; Pediatrics and Child Health, Stellenbosch University Faculty of Medicine and Health Sciences, Cape Town, South Africa.
  • Abraham DR; Pediatrics and Child Health, Stellenbosch University Faculty of Medicine and Health Sciences, Cape Town, South Africa.
  • Goussard P; Pediatrics and Child Health, Stellenbosch University Faculty of Medicine and Health Sciences, Cape Town, South Africa pgouss@sun.ac.za.
  • Van Toorn R; Pediatrics and Child Health, Stellenbosch University Faculty of Medicine and Health Sciences, Cape Town, South Africa.
BMJ Case Rep ; 14(8)2021 Aug 11.
Article in English | MEDLINE | ID: covidwho-1354559
ABSTRACT
We report on a unique case of a 7-year-old girl with new onset ocular myasthenia gravis shortly after recovery from multisystem inflammatory syndrome in children (MIS-C) temporally associated with SARS-CoV-2 infection. The diagnosis of myasthenia gravis was based on suggestive symptoms of fatigable bilateral orbital ptosis, diplopia, positive ocular cold compression test and serum acetylcholine receptor antibody positivity, as well as a favourable treatment response to pyridostigmine. The addition of corticosteroids and methotrexate resulted in complete resolution of the ocular signs.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / Myasthenia Gravis Type of study: Case report / Diagnostic study Topics: Long Covid Limits: Child / Female / Humans Language: English Year: 2021 Document Type: Article Affiliation country: Bcr-2021-244102

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / Myasthenia Gravis Type of study: Case report / Diagnostic study Topics: Long Covid Limits: Child / Female / Humans Language: English Year: 2021 Document Type: Article Affiliation country: Bcr-2021-244102