How to Coordinate Vaccination and Social Distancing to Mitigate SARS-CoV-2 Outbreaks
Siam Journal on Applied Dynamical Systems
; 20(2):1135-1157, 2021.
Article
in English
| Web of Science | ID: covidwho-1354592
ABSTRACT
Most countries have started vaccinating people against COVID-19. However, due to limited production capacities and logistical challenges it will take months/years until herd immunity is achieved. Therefore, vaccination and social distancing have to be coordinated. In this paper, we provide some insight on this topic using optimization-based control on an age-differentiated compartmental model. For real-life decision-making, we investigate the impact of the planning horizon on the optimal vaccination/social distancing strategy. We find that in order to reduce social distancing in the long run, without overburdening the health care system, it is essential to vaccinate the people with the highest contact rates first. That is also the case if the objective is to minimize fatalities provided that the social distancing measures are sufficiently strict. However, for short-term planning it is optimal to focus on the high-risk group.
Full text:
Available
Collection:
Databases of international organizations
Database:
Web of Science
Topics:
Vaccines
Language:
English
Journal:
Siam Journal on Applied Dynamical Systems
Year:
2021
Document Type:
Article
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