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SARS-CoV-2 (Covid-19) vaccines structure, mechanisms and effectiveness: A review.
Fathizadeh, Hadis; Afshar, Saman; Masoudi, Mahmood Reza; Gholizadeh, Pourya; Asgharzadeh, Mohammad; Ganbarov, Khudaverdi; Köse, Sükran; Yousefi, Mehdi; Kafil, Hossein Samadi.
  • Fathizadeh H; Department of laboratory sciences, Sirjan School of Medical Sciences, Sirjan, Iran.
  • Afshar S; Department of Animal Biology, Faculty of Natural Science, University of Tabriz, Tabriz, Iran.
  • Masoudi MR; Department of Internal Medicine, Sirjan School of Medical Sciences, Sirjan, Iran.
  • Gholizadeh P; Research Center for Pharmaceutical Nanotechnology, Tabriz University of Medical Sciences, Iran.
  • Asgharzadeh M; Biotechnology Research Center, Tabriz University of Medical Sciences, Iran.
  • Ganbarov K; Department of Microbiology, Baku state University, Baku, Azerbaijan.
  • Köse S; Department of Infectious Diseases and Clinical Microbiology, University of Health Sciences, Tepecik Training and Research Hospital, Izmir, Turkey.
  • Yousefi M; Stem Cell Research Center, Tabriz University of Medical Sciences, Iran. Electronic address: yousefime@tbzmed.ac.ir.
  • Kafil HS; Drug Applied Research Center, Faculty of Medicine, Tabriz University of Medical Sciences, Iran. Electronic address: Kafilhs@tbzmed.ac.ir.
Int J Biol Macromol ; 188: 740-750, 2021 Oct 01.
Article in English | MEDLINE | ID: covidwho-1356252
ABSTRACT
The world has been suffering from COVID-19 disease for more than a year, and it still has a high mortality rate. In addition to the need to minimize transmission of the virus through non-pharmacological measures such as the use of masks and social distance, many efforts are being made to develop a variety of vaccines to prevent the disease worldwide. So far, several vaccines have reached the final stages of safety and efficacy in various phases of clinical trials, and some, such as Moderna/NIAID and BioNTech/Pfizer, have reported very high safety and protection. The important point is that comparing different vaccines is not easy because there is no set standard for measuring neutralization. In this study, we have reviewed the common platforms of COVID-19 vaccines and tried to present the latest reports on the effectiveness of these vaccines.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Vaccines / COVID-19 Type of study: Experimental Studies / Prognostic study Topics: Vaccines Limits: Animals / Humans Language: English Journal: Int J Biol Macromol Year: 2021 Document Type: Article Affiliation country: J.ijbiomac.2021.08.076

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Vaccines / COVID-19 Type of study: Experimental Studies / Prognostic study Topics: Vaccines Limits: Animals / Humans Language: English Journal: Int J Biol Macromol Year: 2021 Document Type: Article Affiliation country: J.ijbiomac.2021.08.076