Immunosuppressive therapy in childhood-onset arrhythmogenic inflammatory cardiomyopathy.
Pacing Clin Electrophysiol
; 44(3): 552-556, 2021 03.
Article
in English
| MEDLINE | ID: covidwho-1358629
ABSTRACT
We present, to our knowledge, the first case of immunosuppressive therapy (IST) application in a 12-year-old child with arrhythmogenic inflammatory cardiomyopathy resulting from the overlap between autoimmune myocarditis and primary arrhythmogenic cardiomyopathy. Indication to off-lable IST was compelling, because of recurrent drug-refractory ventricular arrhythmias (VAs). We show that IST was feasible, safe, and effective on multiple clinical endpoints, including symptoms, VA recurrences, and T-troponin release. Remarkably, all diagnostic and therapeutic strategies were worked out by a dedicated multidisciplinary team, including specialized pediatric immunologists.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Immunosuppression Therapy
/
Arrhythmogenic Right Ventricular Dysplasia
Type of study:
Case report
/
Observational study
/
Prognostic study
/
Randomized controlled trials
Limits:
Child
/
Humans
/
Male
Language:
English
Journal:
Pacing Clin Electrophysiol
Year:
2021
Document Type:
Article
Affiliation country:
Pace.14153
Similar
MEDLINE
...
LILACS
LIS