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Worsened Parkinson's Disease Progression: Impact of the COVID-19 Pandemic.
Ineichen, Christian; Baumann-Vogel, Heide; Sitzler, Matthias; Waldvogel, Daniel; Baumann, Christian R.
  • Ineichen C; Department of Neurology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
  • Baumann-Vogel H; Department of Neurology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
  • Sitzler M; Department of Neurology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
  • Waldvogel D; Department of Neurology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
  • Baumann CR; Department of Neurology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
J Parkinsons Dis ; 11(4): 1579-1583, 2021.
Article in English | MEDLINE | ID: covidwho-1359153
ABSTRACT
Whilst some studies investigated the impact of viral infection or reduced access to medication during the COVID-19 pandemic in patients with Parkinson's disease (PD), data on the effects of pandemic restrictions are still scarce. We retrospectively analyzed motor symptoms of longitudinally followed PD patients (n = 264) and compared motor disease progression before and during the COVID-19 pandemic. Additionally, we performed a trend analysis of the yearly evolution of motor symptoms in 755 patients from 2016 until 2021. We observed a worsening of motor symptoms and a significantly increased motor disease progression during pandemic-related restrictions as compared to before the COVID-19 outbreak.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Exercise / Disease Progression / Symptom Flare Up / Physical Distancing / COVID-19 Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study Limits: Aged / Female / Humans / Middle aged Language: English Journal: J Parkinsons Dis Year: 2021 Document Type: Article Affiliation country: JPD-212779

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Exercise / Disease Progression / Symptom Flare Up / Physical Distancing / COVID-19 Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study Limits: Aged / Female / Humans / Middle aged Language: English Journal: J Parkinsons Dis Year: 2021 Document Type: Article Affiliation country: JPD-212779