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SARS-CoV-2 immunogenicity in individuals infected before and after COVID-19 vaccination: Israel, January-March 2021.
Abu Jabal, Kamal; Ben-Amram, Hila; Beiruti, Karine; Brimat, Ira; Abu Saada, Ashraf; Bathish, Younes; Sussan, Christian; Zarka, Salman; Edelstein, Michael.
  • Abu Jabal K; Ziv Medical Centre, Safed, Israel.
  • Ben-Amram H; Bar-Ilan University, Safed, Israel.
  • Beiruti K; Ziv Medical Centre, Safed, Israel.
  • Brimat I; Ziv Medical Centre, Safed, Israel.
  • Abu Saada A; Ziv Medical Centre, Safed, Israel.
  • Bathish Y; Bar-Ilan University, Safed, Israel.
  • Sussan C; Ziv Medical Centre, Safed, Israel.
  • Zarka S; Ziv Medical Centre, Safed, Israel.
  • Edelstein M; Ziv Medical Centre, Safed, Israel.
Epidemiol Infect ; 149: e239, 2021 08 17.
Article in English | MEDLINE | ID: covidwho-1360170
ABSTRACT
Between December 2020 and March 2021, we measured anti-SARS-CoV-2 IgG titres among 725 Israeli hospital workers vaccinated against COVID-19. Infection post-dose 1 vaccination did not increase IgG titres, and individuals infected post-dose 1 had IgG levels comparable to never-infected individuals who received a single dose, lower than fully vaccinated, never-infected individuals. This suggests dose 2, currently not offered to those infected post-dose 1, may be required in these individuals. Larger studies should confirm whether individuals infected post-dose 1 need the second.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Immunization Schedule / COVID-19 Vaccines / SARS-CoV-2 / COVID-19 Type of study: Experimental Studies / Observational study Topics: Vaccines Limits: Humans Country/Region as subject: Asia Language: English Journal: Epidemiol Infect Journal subject: Communicable Diseases / Epidemiology Year: 2021 Document Type: Article Affiliation country: S0950268821001928

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Immunization Schedule / COVID-19 Vaccines / SARS-CoV-2 / COVID-19 Type of study: Experimental Studies / Observational study Topics: Vaccines Limits: Humans Country/Region as subject: Asia Language: English Journal: Epidemiol Infect Journal subject: Communicable Diseases / Epidemiology Year: 2021 Document Type: Article Affiliation country: S0950268821001928