The role of NK cells in fighting the virus infection and sepsis.
Int J Med Sci
; 18(14): 3236-3248, 2021.
Article
in English
| MEDLINE | ID: covidwho-1360866
ABSTRACT
Natural killer cells, one of the important types of innate immune cells, play a pivotal role in the antiviral process in vivo. It has been shown that increasing NK cell activity may promote the alleviation of viral infections, even severe infection-induced sepsis. Given the current state of the novel coronavirus (SARS-CoV-2) global pandemic, clarifying the anti-viral function of NK cells would be helpful for revealing the mechanism of host immune responses and decipher the progression of COVID-19 and providing important clues for combating this pandemic. In this review, we summarize the roles of NK cells in viral infection and sepsis as well as the potential possibilities of NK cell-based immunotherapy for treating COVID-19.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Killer Cells, Natural
/
Sepsis
/
Host-Pathogen Interactions
/
COVID-19
Limits:
Humans
Language:
English
Journal:
Int J Med Sci
Journal subject:
Medicine
Year:
2021
Document Type:
Article
Affiliation country:
Ijms.59898
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