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Prevalence and clinical consequences of atelectasis in SARS-CoV-2 pneumonia: a computed tomography retrospective cohort study.
Mingote, Álvaro; Albajar, Andrea; García Benedito, Paulino; Garcia-Suarez, Jessica; Pelosi, Paolo; Ball, Lorenzo; García-Fernández, Javier.
  • Mingote Á; Anaesthesia, Critical Care Department and Pain Unit, Puerta de Hierro Universitary Hospital - Majadahonda, c/Manuel de Falla, 1, 28222, Madrid, Spain. alvaro.mingote.llado@gmail.com.
  • Albajar A; Autonomous University of Madrid, Madrid, Spain. alvaro.mingote.llado@gmail.com.
  • García Benedito P; Anaesthesia, Critical Care Department and Pain Unit, Puerta de Hierro Universitary Hospital - Majadahonda, c/Manuel de Falla, 1, 28222, Madrid, Spain.
  • Garcia-Suarez J; Radiodiagnostic Unit, Puerta de Hierro Universitary Hospital - Majadahonda, Madrid, Spain.
  • Pelosi P; Anaesthesia, Critical Care Department and Pain Unit, Puerta de Hierro Universitary Hospital - Majadahonda, c/Manuel de Falla, 1, 28222, Madrid, Spain.
  • Ball L; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy.
  • García-Fernández J; Anesthesia and Critical Care, IRCCS for Oncology and Neurosciences, San Martino Policlinico Hospital, Genoa, Italy.
BMC Pulm Med ; 21(1): 267, 2021 Aug 17.
Article in English | MEDLINE | ID: covidwho-1362053
ABSTRACT

BACKGROUND:

The aim of the study is to estimate the prevalence of atelectasis assessed with computer tomography (CT) in SARS-CoV-2 pneumonia and the relationship between the amount of atelectasis with oxygenation impairment, Intensive Care Unit admission rate and the length of in-hospital stay. PATIENTS AND

METHODS:

Two-hundred thirty-seven patients admitted to the hospital with SARS-CoV-2 pneumonia diagnosed by clinical, radiology and molecular tests in the nasopharyngeal swab who underwent a chest computed tomography because of a respiratory worsening from Apr 1 to Apr 30, 2020 were included in the study. Patients were divided into three groups depending on the presence and amount of atelectasis at the computed tomography no atelectasis, small atelectasis (< 5% of the estimated lung volume) or large atelectasis (> 5% of the estimated lung volume). In all patients, clinical severity, oxygen-therapy need, Intensive Care Unit admission rate, the length of in-hospital stay and in-hospital mortality data were collected.

RESULTS:

Thirty patients (19%) showed small atelectasis while eight patients (5%) showed large atelectasis. One hundred and seventeen patients (76%) did not show atelectasis. Patients with large atelectasis compared to patients with small atelectasis had lower SatO2/FiO2 (182 vs 411 respectively, p = 0.01), needed more days of oxygen therapy (20 vs 5 days respectively, p = 0,02), more frequently Intensive Care Unit admission (75% vs 7% respectively, p < 0.01) and a longer period of hospitalization (40 vs 14 days respectively p < 0.01).

CONCLUSION:

In patients with SARS-CoV-2 pneumonia, atelectasis might appear in up to 24% of patients and the presence of larger amount of atelectasis is associated with worse oxygenation and clinical outcome.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Pulmonary Atelectasis / Tomography, X-Ray Computed / COVID-19 / Hypoxia Type of study: Cohort study / Diagnostic study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Long Covid Limits: Aged / Female / Humans / Male Country/Region as subject: Europa Language: English Journal: BMC Pulm Med Year: 2021 Document Type: Article Affiliation country: S12890-021-01638-9

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Pulmonary Atelectasis / Tomography, X-Ray Computed / COVID-19 / Hypoxia Type of study: Cohort study / Diagnostic study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Long Covid Limits: Aged / Female / Humans / Male Country/Region as subject: Europa Language: English Journal: BMC Pulm Med Year: 2021 Document Type: Article Affiliation country: S12890-021-01638-9