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The origins of SARS-CoV-2: A critical review.
Holmes, Edward C; Goldstein, Stephen A; Rasmussen, Angela L; Robertson, David L; Crits-Christoph, Alexander; Wertheim, Joel O; Anthony, Simon J; Barclay, Wendy S; Boni, Maciej F; Doherty, Peter C; Farrar, Jeremy; Geoghegan, Jemma L; Jiang, Xiaowei; Leibowitz, Julian L; Neil, Stuart J D; Skern, Tim; Weiss, Susan R; Worobey, Michael; Andersen, Kristian G; Garry, Robert F; Rambaut, Andrew.
  • Holmes EC; Marie Bashir Institute for Infectious Diseases and Biosecurity, School of Life and Environmental Sciences and School of Medical Sciences, The University of Sydney, Sydney, NSW 2006, Australia. Electronic address: edward.holmes@sydney.edu.au.
  • Goldstein SA; Department of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA.
  • Rasmussen AL; Vaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada.
  • Robertson DL; MRC-University of Glasgow Centre for Virus Research, Glasgow G61 1QH, UK.
  • Crits-Christoph A; Department of Plant and Microbial Biology, University of California-Berkeley, Berkeley, CA 94704, USA.
  • Wertheim JO; Department of Medicine, University of California-San Diego, La Jolla, CA 92093, USA.
  • Anthony SJ; Department of Pathology, Microbiology, and Immunology, University of California-Davis School of Veterinary Medicine, Davis, CA 95616, USA.
  • Barclay WS; Department of Infectious Disease, Imperial College, London W2 1PG, UK.
  • Boni MF; Center for Infectious Disease Dynamics, Department of Biology, The Pennsylvania State University, University Park, PA 16802, USA.
  • Doherty PC; Department of Microbiology and Immunology, The University of Melbourne at the Doherty Institute, 792 Elizabeth Street, Melbourne, VIC 3000, Australia.
  • Farrar J; The Wellcome Trust, London NW1 2BE, UK.
  • Geoghegan JL; Department of Microbiology and Immunology, University of Otago, Dunedin 9010, New Zealand; Institute of Environmental Science and Research, Wellington 5022, New Zealand.
  • Jiang X; Department of Biological Sciences, Xi'an Jiaotong-Liverpool University (XJTLU), Suzhou, China.
  • Leibowitz JL; Department of Microbial Pathogenesis and Immunology, Texas A&M University, College Station, TX 77807, USA.
  • Neil SJD; Department of Infectious Diseases, King's College London, Guy's Hospital, London SE1 9RT, UK.
  • Skern T; Max Perutz Labs, Medical University of Vienna, Vienna Biocenter, Dr. Bohr-Gasse 9/3, 1030 Vienna, Austria.
  • Weiss SR; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Worobey M; Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ 85721, USA.
  • Andersen KG; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Garry RF; Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA 70112, USA; Zalgen Labs, Germantown, MD 20876, USA.
  • Rambaut A; Institute of Evolutionary Biology, University of Edinburgh, Edinburgh EH9 3FL, UK. Electronic address: a.rambaut@ed.ac.uk.
Cell ; 184(19): 4848-4856, 2021 09 16.
Article in English | MEDLINE | ID: covidwho-1363914
ABSTRACT
Since the first reports of a novel severe acute respiratory syndrome (SARS)-like coronavirus in December 2019 in Wuhan, China, there has been intense interest in understanding how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in the human population. Recent debate has coalesced around two competing ideas a "laboratory escape" scenario and zoonotic emergence. Here, we critically review the current scientific evidence that may help clarify the origin of SARS-CoV-2.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 Type of study: Reviews Limits: Animals / Humans Language: English Journal: Cell Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 Type of study: Reviews Limits: Animals / Humans Language: English Journal: Cell Year: 2021 Document Type: Article