In-hospital outcomes of COVID-19 infection in patients with underlying cardiovascular disease.
Expert Rev Cardiovasc Ther
; 19(9): 871-876, 2021 Sep.
Article
in English
| MEDLINE | ID: covidwho-1364675
ABSTRACT
BACKGROUND:
The effects of cardiovascular comorbidities on outcomes in COVID-19 hospitalized patients has not been well studied.METHODS:
This is a hospital-based study evaluating the effects of CVD on the outcomes in patients admitted with COVID-19. Clinical outcomes were studied in patients with and without CVD.RESULTS:
Eighty-seven patients had CVD, and 193 patients had no history of CVD. Ischemic heart disease was the most common CVD (63%). When compared with patients with no CVD, those with CVD had higher mortality (29% vs 9%, p < 0.001), discharge to a skilled nursing facility (SNF) (36% vs 15%, p < 0.001), and change of code status to 'do not resuscitate' (41% vs 14%, p < 0.001). The odds for mortality were high with ischemic heart disease (OR 3.6, 95% CI 1.8-7.3, p < 0.001), and systolic heart failure (OR 3.8,95% CI 1.2-12.3, p = 0.02). Patients in the CVD group were more likely to have incident atrial fibrillation (22% vs 3%, p < 0.001), type 2 Mi (17% vs 6%, p = 0.002), high BNP (57% vs 14%, p < 0.001), acute kidney injury (64% vs 29%, p < 0.001), and any type of circulatory shock (27% vs 12%, p = 0.001).CONCLUSION:
CVD is associated with increased mortality, myocardial injury, arrhythmias, and discharges to an SNF.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Cardiovascular Diseases
/
COVID-19
Type of study:
Experimental Studies
/
Observational study
/
Prognostic study
Limits:
Humans
Language:
English
Journal:
Expert Rev Cardiovasc Ther
Journal subject:
Vascular Diseases
/
Cardiology
/
Therapeutics
Year:
2021
Document Type:
Article
Affiliation country:
14779072.2021.1970532
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